Asthma

Question 1

Intermittant asthma signs and tx

Answer 1

less than 2 days per week and can treat intermittently with ICS + LABA/SABA

Question 2

Mild asthma signs and tx

Answer 2

greater than 2 days per week but not daily. want to tx daily with ICS

Question 3

moderate asthma

Answer 3

daily exacerbations, would do daily low dose ICS/LABA

Question 4

severe asthma

Answer 4

increase ics dose until controlled, still ICS + LABA daily

Question 5

proair/ventolin

Answer 5

albuterol, a SABA

Question 6

salmeterol

Answer 6

LABA

Question 7

QVAR

Answer 7

betamethasone, ICS

Question 8

Pulmicort

Answer 8

Budosenide, ICS

Question 9

symbicort

Answer 9

bucosenids (ICS) + formetalol (LABA)

Question 10

advair

Answer 10

fluticasone (ICS) + salmetarol (LABA)

Question 11

breo

Answer 11

fluticasone (ICS) + vilanterol (LABA)

Question 12

dulera

Answer 12

mometasone (ICS) + formoterol (LABA)

Question 13

ICS s/e

Answer 13

thrush, dysphonia, cough

Question 14

saba s/e

Answer 14

nervousness, tremor, tachycardia, palpitations, cough, hyperglycemia, decreased potassium

Question 15

laba boxed warning

Answer 15

increased risk of asthma related deaths if used alone

Question 16

spiriva

Answer 16

tiotropium (LAMA)

Question 17

flovent

Answer 17

fluticasone (1/2), ICS

Question 18

Arnuity

Answer 18

fluticasone (2/2), ICS

Question 19

Which ICS/LABA can be used for rescue due to its shorter onset of action

Answer 19

symbicort (budosenide + formeterol) and dulera (mometasone + formetorol)

**formetarol

Question 20

What kind of inhaler is DPI?

Answer 20

diskus, ellipta, pressair, handihaler, flexhaler, neohaler, respiclock

Question 21

HFA and Respomat is what kind of inheper

Answer 21

MDI

Question 22

singulair

Answer 22

monteleukast

Question 23

zileuton moa

Answer 23

inhibits leukotriene formation

Question 24

boxed warning montelukast

Answer 24

a leukotriene modifying agent, boxed warning neuropsychiatric effects

Question 25

monteleukast granual administration

Answer 25

can be administered directly in the mouth or dissolved in a small amount of breast milk or formula or mixed with applesauce, carrots, rice, or ice cream. use within 15 min of opening.

Question 26

theophyline dosing weight

Answer 26

IBW

Question 27

converting between aminophyline to theophyline

Answer 27

ATM -> multiply by .8 and vice versa

Question 28

theophyline theraputic range

Answer 28

5-15 mcg/mL

Question 29

theophyline moa

Answer 29

blocks PDE resulting in an increase in cAMP and bronchodilation

Question 30

kinetics of theophyline

Answer 30

small increase in dose may result in massive increase in concentration and is metabolized (a substrate of) by CYP1A2 and Cyp3A4, also affected by CHF/liver dz and high protein diet/low carb

Question 31

theophyline tox

Answer 31

vomiting, arrhythmias, seizures

Question 32

xolair

Answer 32

omalizumab

Question 33

what drug is indicatd for allergic asthma in patients with a positive skin test

Answer 33

xolair/omalizumab which is a monocolonial antibody that inhibits IgE binding

Question 34

boxed warning for omalizumab

Answer 34

anaphylaxis

Question 35

which ics is preferred in pregnancy

Answer 35

budosenide (pulmicort)

Question 36

how to administer xolair

Answer 36

omilizuman, sQ in a healthcare setting under supervision due to risk of anaphalaxzis

Question 37

dupillusumab, mepolizumab, resilizumab, and benralizumab

Answer 37

il receptor antagonsts indicated for eisinophillic phenotype (all il5 except dupilizumab)

Question 38

resilizumab administration

Answer 38

iv with boxed warning for anaphylaxis

Question 39

benralizumab

Answer 39

sc every 8 weeks

Question 40

dupolumab

Answer 40

sc (il4/il3)

Question 41

order of inhalers

Answer 41

SABA1st, then LABA or LAMA, then ICS (60 seconds in between)

Question 42

red zone percent

Answer 42

less than 50% of personal best

Question 43

how to administer MDI

Answer 43

shake for 5 seconds before each spray, prime, breathe in slowly and deeply and hold for 10 seconds. Clean mouthpiece with rinsing once weekly. (for dulera and symbacort just wipe)

Question 44

Respiclick administration

Answer 44

Do not shake. No button. opening cap loads dose, do not open and close, breathe in deeply (a dpi) and hold for 10 seconds

Question 45

pulmacort flexhaler administration

Answer 45

Twisting loads dose. a dpi so breathe in deeply and forcefully and no need to prime. An ICS so rinse with water.

Question 46

advair discus counseling

Answer 46

hold like a hamburger. lever loads dose. a dpi so breathe in quickly and deeply. rinse and spit because ics.

Question 47

how long should ampules be used after opening

Answer 47

2 weeks