Astroviridae Flashcards Preview

RUSVM Virology Spring17 > Astroviridae > Flashcards

Flashcards in Astroviridae Deck (10)
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1
Q

What family of viruses is second to rotaviruses in causing diarrhea?

A

Astroviridae

2
Q

In what animals do viruses from the family astroviridae cause fatal disease?

A

birds

3
Q

What are the two genera of astroviridae and who are the hosts?

A

Avastrovirus: birds (chicken, duck, turkey)

Mamastroviruses: mammals

4
Q

What shape are viruses in the astroviridae family and are they enveloped?

A

Star-like appearance
Icosahedral symmetry

Non-enveloped

5
Q

Astroviridae viruses have ______ sense, linear, _______ stranded RNA

A

Positive sense

single stranded

6
Q

T/F: Astroviridae viruses are resistant to low pH and lipid solvents

A

TRUE

7
Q

Where do astroviridae viruses replicate in the cell?

A

Cytoplasm

*direct translation of proteins

8
Q

Who does Turkey astrovirus target?

A

Young turkeys 1-3weeks old

9
Q

What clinical signs will you see in a turkey with astrovirus?

A

Mild dz: low mortality but persistent infections = poor growing

Diarrhea, listlessness, nervousness, stunted growth

10
Q

What pathology occurs in turkey astrovirus infections?

A

Intestines and ceca are dilated and filled with fluid***
Hyperplasia of the crypt enterocytes
*virus replication in enterocytes lining the vili
*maldigestion –> DHR