ATI Unit 2 Parkison's Disease Flashcards Preview

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Flashcards in ATI Unit 2 Parkison's Disease Deck (7):
1

What is Parkinson's disease?

- neurodegenerative condition where basal ganglia are overstimulated causing overproduction of ACl and substantia nigra doesn't produce enough dopamine
4 main features
1) bradykinesia (slow movemnt)
2) tremors
3) muscle rigidity
4) postural instability

- either decrease ACl or increase Dopamine

2

risk factors for parkinson's

- male between 40-60
- taking anti-psychotics
- genetic

3

manifestations of parkinson's

- stooped posture
- shuffling gate
- hand tremors
- slow speech
- mask-like face
- muscle rigidity
- postural instibility
- mood swings
- drooling
- dementia
- PILL-rolling

*diagnosis made based on symptoms

4

things to remember

- liquid food thickeners
- communication/muscle strengthening
- exercise, pace yourself
- frequent rest periods

5

meds for parkinson's

1) dopaminergics
- levodopa-carbidopa (Sinemet) converted to dopamine in brain

2) dopamine agonists
- bromocriptine (Parlodel), ropinirole (Requip), pramipexole (Mirapex) - ortho hypo, dyskinesia, hallucinations

3) anticholinergics - for tremors/rigidity remember can't see can't spit etc
- benztropine (Cogentin), trihexyphenidyl (Artane)

4) catechol O-methyltransferase (COMT) inhibitors
- decrease breakdown of levodopa
- diarrhea
- dark urine is normal finding

5) antivirals like amantadine (Symmetrel) stimulate release of DE and reuptake prevention
- monitor for swollen ankles and discoloration of skin
- may also experience atropine-like effects

6

surgical interventions for parkinson's

1) stereotactic pallidotomy
2) deep brain stimulation - implant with magnet

7

Complications

1) aspiration pneumonia
- dysphagia cause

2) altered cognition (dementia, memory stuff)