Auditory System 2 (Section 4) Flashcards

0
Q

Cell bodies of auditory CN VIII neurons lie in what ganglion

A

Spiral ganglion

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1
Q

The mechanical deformation of the hair cells on the basilar membrane causes what?

A

The opening of ion channels in the hair cells

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2
Q

What is responsible for the transduction process in the ear

A

Hair cells

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3
Q

WHere do the axons of the auditory CN VIII terminate?

A

Cochlear nuclei

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4
Q

What part of the cochlea receive high frequency sounds

A

Base of the cochlea

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5
Q

Apex of cochlea have what frequency of sounds

A

Low frequency sounds

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6
Q

Which portion of the cochlea have stereocilia that are short and stiff

A

Base of the cochlea

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7
Q

Hair cells at apex are twice as long as base of cochlea

A

True

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8
Q

How many rows of hair cells are on the inner part

A

Single row

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9
Q

How many hair cells are on the outer part

A

Three rows

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10
Q

Action potentials traveling down the central process of the cochlear nerve reach what nuclei?

A

Dorsal and Ventral cochlear nuclei in the Medulla

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11
Q

Fibers in the 8CSLIMA pathway decussate where?

A

Lower pons and ascend in the lateral lemniscus

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12
Q

Of those fibers that decussate in the 8CSLIMA pathway where do they synapse?

A

Superior Olivary Nuclear complex

Reticular Formation

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13
Q

Some fibers ascend uncrossed in what?

A

Ipsilateral lateral lemniscus

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14
Q

A unilateral lesion of the central auditory pathway causes more hearing loss on which side of lesion

A

Contralateral or the opposite side of the lesion

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15
Q

Fibers in the lateral lemniscus (8CSLIMA) synapse where?

A

Inferior colliculus

16
Q

After synapsing in the Inferior Colliculus, axons go to what part of the diencephalon?

A

Medial Geniculate

17
Q

Neurons in the medial geniculate send axons to where?

A

Primary Auditory Cortex (Brodmann’s areas 41 and 42)

18
Q

Primary auditory cortex functions how?

A

Conscious hearing of sound

19
Q

Superior Olivary nucleus and Inferior Colliculus function

A

Orientation/localization of sound

20
Q

Reticular Formation function

A

CNS activation/alertness

21
Q

Tensor Tympani muscle is innervated by what nerve?

A

CN V

22
Q

Tensor Tympani muscle function

A

Dampen vibration of tympanic membrane in response to loud noise

23
Q

Nerve and function of Stapedius muscle

A

CN VII

Function to dampen vibration of stapes in response to loud noise

24
Q

Conductive deafness is:

A

Caused by interruption of the passage of sound waves through the external or middle ear

25
Q

Three things that can contribute to conductive deafness

A
  1. Obstruction by a foreign body in the external auditory meatus
  2. Otosclerosis - fixation of the stapes due to excessive bone growth
  3. Otitis media - inflammation of middle ear. Common cause of meningitis and most common cause of brain abscesses
26
Q

Sensorineural deafness - 5 causes

A
  1. Disease of the cochlea, CN VIII, or the central auditory connections
  2. Action of drugs and toxins
  3. Rubella infection in utero, syphilis…
  4. Presbycusis - hearing loss that occurs with aging
  5. Acoustic neuroma - tumor of CN VIII
27
Q

How would a tumor affect hearing?

A

A tumor of CN VIII in the cerebellopontine angle, near the brainstem exit of CN VIII

28
Q

2 causes of Hyperacusis

A
  1. Damage of CN V preventing tympani muscle from dampening sounds
  2. Damage to CN VII preventing stapedius muscle from dampening sounds
29
Q

What is Tinnitus?

A

Abnormal sounds (ringing, hissing, roaring, buzzing, or humming)

30
Q

4 causes of Tinnitus

A

Acoustic neuroma
Irritation of spiral organ of Corti in the cochlea
Irritation of CN VIII
Overproduction of endolymph

31
Q

Meniere’s Syndrome cause

A

overproduction of endolymph or inability to absorb endolymph

32
Q

Unilateral lesion of ascending auditory pathway causes?

A

bilateral diminution of hearing but MORE marked on contralateral side