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Flashcards in Autoimmunity Deck (8)
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1

Autoimmune disease

(both organ specific & non-organ specific)

tissue/organ damage - cellular/humoral immune mech - direct against auto/self-Ag

2

Estrogen is damaging to Tolerance - T or F?

True - thus Autoimmune disease higher in women

3

Immune sys avoids producing damaging reactions against self Ag.

Tolerance

4

Deletion of autoreactive T + B cells during cell maturation

Central tolerance

5

Inhibit the act of autoreactive cells which escape central tolerance

Peripheral tolerance

6

Tolerance is one of the cardinal features of adaptive immunity - T or F?

True
breakdown of 1 or more tolerance process= autoimmune disease

7

Non-organ specific autoimmune disorders

CT disorders

8

Organ specific autoimmune disorders

autoimmune endocrine disorder