Flashcards in Autoimmunity Deck (8)
(both organ specific & non-organ specific)
tissue/organ damage - cellular/humoral immune mech - direct against auto/self-Ag
Estrogen is damaging to Tolerance - T or F?
True - thus Autoimmune disease higher in women
Immune sys avoids producing damaging reactions against self Ag.
Deletion of autoreactive T + B cells during cell maturation
Inhibit the act of autoreactive cells which escape central tolerance
Tolerance is one of the cardinal features of adaptive immunity - T or F?
breakdown of 1 or more tolerance process= autoimmune disease
Non-organ specific autoimmune disorders