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Flashcards in Intro to Fungi Deck (35):
1

Fungi gets __ from breaking down __ chemo-organotrophic eukaryote
Lacks _____ and forms ____

1. energy
2. chemicals
3. chlorophyll
4. spores

Cell wall - polysaccharides, chitin or cellulose
Membrane - ergosterol(major sterol)

2

Classification is based on

morphology

major types as moulds, yeasts or mushrooms

3

Fungi that favour a unicellular habit

yeast

4

Fungi are a significant cause of

non-fatal diseases

5

Epidermophyton causes

athlete’s foot

6

Thrush is caused by

Candida spp.

7

pityriasis versicolor is caused by ........ They can form .....

Malassezia spp. (yeast)
hyphae

8

Microsporum causes

athlete’s foot

9

Trichophyton causes

athlete’s foot (mould)

10

Dermatophytes are _____ which can cause infections of the skin, hair, and nails due to their ability to utilize _____ . They also have the ability to form .....

moulds
keratin
hyphae

ringworm inf
tinea .....

11

Epidermophyton, Microsporum and Trichophyton are _____ and cause


Dermatophytosis
athlete foots (mould)

12

______species infect deep organs of patients with immune dysfunction, e.g. after abdominal surgery, burns, etc. (cases often in ICU)

Candida (yeast)

13

______ spp. infect deep organs of patients undergoing e.g. chemotherapy, stem cell transplantation

Aspergillus (mould)

14

_____ contributes to pathogenicity of fungal inf

Host factors

environment, broad spect anti-biotic, immune suppression (disease , iatrogenesis or both)

15

Which candida sp. have hyphae? What colour colony do they form in chrom agar?

C. albicans (mainly oral)
Green

16

Candida in vagina is caused by ...... and shows up ...... in selective chrom agar

Tropicalis
Blue

17

Candida in skin is caused by ...... and shows up ...... in selective chrom agar

C. glabrata
pink

18

Candida in nails is caused by ...... and shows up ...... in selective chrom agar

C.Krusei
white

19

Candida reside in GI as a commensal flora and most infection are ........

endogenous

20

Candida infection are mostly superficial (nails, skin etc.) and some are disseminated - these types are called......

Deep seated - occurs in immuno-compromised

21

Spore formation occurs in ...

molds

22

Chronic mucocutaneous candida inf occurs in ....... and the disease is called ...........

endocrine and immune dys patients
APECED (autoimmune polyendocrinopathy-candidiasis ectodermal dystrophy

23

Aspergillus (mould) is present in environment and inhalation of ....... can cause disease. It is .... as it can penetrate the blood vessel walls

conidia
angioinvasive

24

Asp fumigatus causes

simple asthma

25

Asp flavus causes

asthma with eosinophilia

26

Invasive pulmonary aspergillus could cause ........ malignancy

haematological

27

Cryptococcus (yeast) falls under..... group

Basidiomycetes

28

Cryptococcus neoformans causes ......... cryptococcosis

pulmonary

29

Cryptococcus gattii cause

meningitis - esp in patients with AIDS

30

.............. stain is used for direct smear e.g. vaginal

PAS (periodic acid schiff)

31

Common diagnostic is histopath and high-resolution ......

CT scan

e.g. Dermatophytes in skin scales (KOH prep)

32

Echinocandins

bind to ergosterols in cell wall

33

Polyenes

target membrane

34

Azoles

inhibit ergosterols syn

35

Allylamines

inhibit ergosterols syn