Flashcards in Autoimmunity diagnosis Deck (10):
What is the definition of sensitivity in this context?
[a/(a+c)]- measure of how good is the test in identifying people with the disease
What is the definition of specificity in this context?
[d/(b+d)]- measure of how good is the test at correctly defining people without the disease
What is a Positive predictive value?
[a/(a+b)]-The proportion of people with a positive test who have the target disorder
What is a Negative predictive value?
d/(c+d) The proportion of people with a negative test who do not have the target disorder.
What are the non-specific markers of systemic inflammation?
How is anti-dsDNA tested for?
Crithidia luciliae assay (protosoa)
How are ENA's tested for?
Combination of antigens
Which is more specific for Rheumatoid arthritis - RF or ACPA?
ACPA (95% compared to 70%)
What is the gold standard for diagnosis in most cases?