Autonomic Nervous System Drugs for the Respiratory System Flashcards Preview

CVRH Exam 3 > Autonomic Nervous System Drugs for the Respiratory System > Flashcards

Flashcards in Autonomic Nervous System Drugs for the Respiratory System Deck (22):
1

Why must B2 selective agonist be inhaled for bronchodilation?

Because there are B2 receptors in the heart also which can cause arrhythmia

2

What occurs if you give a patient a beta 1 agonist when they are hypoxic?

It causes lethal arrhythmias

3

What are long acting beta 2 selective agents (inhaler)?

Salmeterol
Formoterol (Ford motor oil)

4

What can excess amounts of a beta 2 agonist inhaler cause?

Tachycardia and cardiac arrhythmia

5

What occurs with anti-cholinesterase overdose?

Mucous build-up mimicking asthma

6

What is the methacholine challenge test?

Testing of FEV1 for asthma

7

What is methacholine?

Acetylcholine derivative that is less susceptible to cholinesterase

8

How is the methacholine test carried out and interpreted?

Increasing amounts of methacholine administered; if FEV1 falls by 20% with the max dose of methacholine administered

9

What is ipratropium?

A short-acting anticholinergic (inhaled)

10

What is tiotropium?

Long acting anticholinergic (inhaled)

11

What does inhaling anticholinergics cause?

Inhibiting of parasympathetic nervous systems action on the lungs

12

What are the most effective long-term therapy for chronic asthma?

Glucocorticoids

13

Why are glucocorticoids only prophylactic?

Because they are slow and take hours to bronchodilate

14

How are glucocorticoids administered?

Nasal inhalation (oral are dangerous)

15

What happens if glucocorticoids are inhaled without a spacer?

The majority goes to mouth and GI causing fungal stomatitis (thrush); decrease bodies ability to fight fungus

16

When glucocorticoids are prescribed orally what is the stipulation?

They are given in decreasing doses to decrease the side effects

17

What are inhaled glucocorticoids?

Budesonide
Fluticasone

18

Where is serotonin found outside the brain?

In the GI tract a part of the enteric nervous system

19

What are SSRIs?

Selective Serotonin Re-uptake Inhibitors

20

What do SSRIs do?

Inhibit re-uptake from neurons

21

What does reserpine do?

Inhibits VMAT from releasing serotonin

22

What is cyproheptadine?

Non-selective H1 and 5-HT2 (serotonin) blocker