Partial pressure of oxygen in alveoli artery and veins?
Alveoli: 100
Artery: 95
Vein: 40
Partial pressure of carbon dioxide in alveoli artery and veins?
Alveoli: 40
Artery: 40
Vein: 46
What occurs to partial pressure of O2 in the lungs in hyper and hypoventilation respectively?
Hyperventilation: increase
Hypoventilation: decrease
How many layers do gases have to diffuse to in order to reach the Hb?
12 layers affecting diffusion constants
What is important to note about the Fick law?
Each can be affected by a diseased condition
Difference in diffusion limited and perfusion limited?
Diffusion limited: abnormal condition in which the gases have to diffuse through a thicker wall (fibrosis; can’t diffuse)
Perfusion limited: dependent on blood flow (more oxygen in capillary only if increased blood flow; gas reaches saturation point in the blood)
How can exercise be diffusion limited?
There is more blood flowing than oxygen being ventilated to saturate the blood
Formula pulse oximeter uses?
SaO2= (HbO2 content/HbO2 capacity)x100%
What do pulse oximeters tell you?
Just concentration of O2 in blood nothing else do not extrapolate knowledge (just don’t)
What is the concentration of 2,3-BPG in pregnant women versus normal?
Higher 2,3-BPG
What Hb can give you an idea of diabetic management indicator?
HbA1c when it is highly glycosylated
What amount of CO2 is dropped off from systemic to lungs?
Systemic 52 mL/dL- pulmonary 48 mL/dL= 4 mL/dL
What is the major way that CO2 is transported in blood?
HCO3-
What is the Haldane effect?
Higher oxygen content decreases the affinity of CO2 for Hb
