autonomic nervous system II Flashcards Preview

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Flashcards in autonomic nervous system II Deck (36):
1

once a somatic neuron release ACh, what type of nicotenic receptor does it bind to?

N1

2

once a parasymp or sym neuron releases ACh, what type of receptor does it bind to?

N2

3

what is the N2 receptor antagonist?

hexamethonium

4

what is the N1 receptor antagonist?

d-tubocurarine

5

in parasympathetic neurons what is the receptor type?

muscarinic cholinergic

6

what is atropine?

a general muscaronic cholinergic receptor antagonist

7

muscarinic cholinergic receptors M1, M3 & M5 linked to?

activation of PLC, increased intracellular calcium and DAG

8

muscarinic cholinergic receptors M2 & M4 linked to?

inhibition of adenylyl cyclase and decreased cAMP generation

9

in regards to parasymp control, what does cranial nerve 3 do?

pupillary constriction

10

in regards to parasymp control, what does cranial nerve 7 do?

lacrmal gland and nasal mucosal secretions
also salivary glands

11

in regards to parasymp control, what does cranial nerve 9 do?

salivary glands

12

in regards to parasymp control, what does cranial nerve 10 do?

GI paralysis/increased motility and sphincter relaxation, bronchial constriction, decreased HR

13

in regards to parasymp control, what does the pelvic splechnics do?

relax ureter and sphincter in conjunction with contraction of the detrusor muscle during urination, rectal emptying and penile erection

14

where does the vagus originate?

dorsal motor nucleus and in some of the nuclus ambiguus (where there is also IX)

15

what are the 4 parasymp pre gang fibers originating in the brain stem?

nerve III (ocuolomotor)
nerve VII (facial)
nerve IX (glossopharyngeal)
nerve X (vagus)

16

what is the nucleus tractus solitarius (NTS)?

it receives visceral afferents and is part of the larger visceral control system

17

what does the myenteric (Auerbach) mucosa plexus control?

gut motility

18

what does the submucosa plexus control?

secretions

19

describe the parasympathetic control on the enteric nervous system

enhances motility and secretions

20

describe the sympathetic control on the myenteric plexus in the gut

Norepinephrine is released from the sympathetic nerve terminals in the myenteric plexus, hyperpolarizing and relaxing the smooth muscle in the gut and causing sphincted constriction

21

describe the parasymp control on micturition

constriction of the detrusor muscle and relaxation of the internal sphincter

22

what 2 types of receptors are in the internal sphincter?

alpha 1 adrenoreceptor for sympathetic
M muscarinic cholinorepector for parasympathetic

23

what 2 types of receptors are in the detrusor muscle?

beta 2 adrenoreceptor for symps
M muscarinic cholinorepector for parasympathetic

24

what five areas of the brain house control centers for autonomic nervous system?

hypothalamus
brainstem
midbrain
pons
medulla

25

what would be the result from a transection of the brain stem just below the medulla?

decrease in arterial blood pressure to less than 1/2 the normal value

26

list some examples when visceral afferents overwhelm cortical function ("nothing else seems to matter")

hunger, nausea, dyspnea, visceral pain, bladder & bowel distention, hypothermia, hyperthermia

27

how can seizures be induced?

from massive sympathetic output and arrhythmias

28

where do the symptoms of fear and panic attacks come from?

initiation of the flight or flight (sympathetic)

29

why does nervousness before a test cause diarrhea?

because there is an imbalance between the PNS and the SNS causing insufficient transit time to reabsorb water

30

Which adrenergic receptor is predominantly found in the heart?

B1

31

In skeletal muscle, there are two types of adrenergic receptors, which causes vasodilation and which causes vasoconstriction?

alpha 1 - vasoconstriction
beta2 - vasodilation

32

Which adrenergic receptor is found in the bronchioles?

B2

33

Which receptor is responsible for erection? ejaculation?

erection - M
ejaculation - alpha1

34

which adrenergic receptors are found in the skin?

alpha

35

Which receptor is responsible for gland secretion?

M

36

Which receptor is responsible for ciliary dilation? Iris dilation?

ciliary - beta
iris - alpha 1

Sympathetic causes pupil DILATION