Flashcards in Resting Potential Deck (12):

1

## What is the membrane voltage equation?

### V=Q/C

2

## How is depolarization achieved?

###
-Reduction in charge separation

-Less negative membrane potential

3

## How is hyperpolarization achieved?

###
-Increase in charge separation

-More negative membrane potential

4

## Which establishes ionic gradients - Ion pumps or ion channels?

### Ion pumps ! active transporters which establish ionic gradients

5

##
Where are the following ions in higher concentration - outside or inside the cell?

1. K+

2. Na+

3. Ca2+

###
1. K+ is higher inside

2. Na+ is higher outside

3. Ca2+ is MUCH higher outside

6

## Is the direction of current flow defined as the direction of net movement of Positive or Negative charge?

### POSITIVE

7

## What is the nernst equation?

###
E=RT/zF Log (X)2/(X)1

or just know:

E=61.5 Log (Koutside/Kinside)

8

## What is the nernst equation used for ?

### To calculate equilibrium potential (theoretical situation mostly)

9

## What is the goldmans equation used for?

### To calculate a steady state potential --> membrane potential (accounts for permeabilitites)

10

## What is the Pna/Pk ratio or alpha of the goldman equation?

### alpha =0.05

11

## What is a result of interstitial hypokalemia (lower K+ concentration)

### Cellular hyperpolarization (more negative)

12