Azathioprine Flashcards
1
Q
What class of drug is azathioprine?
A
Antiproliferative immunosuppressant
2
Q
What are the uses of azathrioprine?
A
- systemic lupus erthymatous + vasculitis
- IBS
- rheumatoid arthritis (weakly)
- atopic dermatitis
- bullous skin disease
- steroid ‘sparing’ drug
3
Q
What is the mechanism of action of azathroprine?
A
Inhibits synthesis of purines needed for DNA+RNA synthesis
4
Q
What are adverse drug reactions of azathioprine?
A
Immunosuppressant:
- risk of malignancy
- hepatitis
- infection
- bone marrow suppression
