B7-067 Limbic System Flashcards

1
Q

taste receptor cells and olfactory receptors can regenerate via […] cells

A

basal

(act as stem cell population)

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2
Q

what taste transductions occur via direct ionic mechanisms? [2]

A

salt (Na+)
sour (H+)

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3
Q

what taste transductions occur via second messenger? [3]

A

sweet
bitter
umami

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4
Q

transduction of taste causes cells to […] and activate neurotransmitter

A

depolarize

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5
Q

CN that carry taste [3]

A

VII
IX
X

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6
Q

CNs mediating taste target the […] nucleus

A

gustatory

(part of solitary)

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7
Q

primary gustatory cortex is located in the […]

A

insula

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8
Q

shearing of olfactory cells at the cribriform plate can result in

A

anosmia

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9
Q

all olfactory transduction is done via […] receptors

A

G-protein coupled

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10
Q

olfactory receptors synapse in the […] of the olfactory bulb

A

glomeruli

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11
Q

[…] tract projects directly to the cortex

A

olfactory

(no synapse in thalamus)

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12
Q

main targets of olfactory pathways [3]

A

amygdala (hypothalamus)
neocortex (OFC)
entorhinal cortex (hippocampus)

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13
Q

loss of olfactory sense

A

anosmia

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14
Q

why can COVID-19 cause anosmia?

A

virus binds to supporting olfactory cells

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15
Q

functions of the limbic system [4]

A

Homeostasis
Olfaction
Memory
Emotions and drives

HOME

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16
Q

many cortical limbic structures represent […] cortical architecture

A

primitive

(less than 6 layers)

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17
Q

hippocampal structure with only 3 layers of cortex

A

allocortex

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18
Q

how many layers of cortex does the neocortex have?

A

6

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19
Q

forms the gradual transition between 3 and 6 layer cortices

A

mesocortex

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20
Q

[…] memory is taken care of by the limbic circuits

A

short term

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21
Q

Papez circuit

A

cingulate cortex –> entorhinal cortex –> hippocampal formation –> fornix –> mammillary body –> anterior nucleus of thalamus

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22
Q

input from sensory association areas and olfactory bulb is consolidated in the […] cortex, then projects to hippocampus

A

entorhinal

(project to dentate gyrus and pyramidal cells)

23
Q

[…] gyrus of the hippocampus maintains the ability to regenerate new neurons into adulthood

24
Q

the […] cells of the hippocampus are extremely sensitive to anoxia

A

pyramidal (CA1-3 areas)

25
the brain's GPS
hippocampus "grid cells" and "place cells"
26
subconscious evaluator of the meaning of stimuli emotional response to the consequence of a situation
amygdala
27
olfactory information is received in the [...] of the amygdala
corticomedial nuclear group
28
visual, auditory, and tactile information is received in the [...] of the amygdala
basolateral nuclear group
29
information from the the solitary nucleus and parbrachial nucleus is received in the [...] of the amygdala
central nucleus
30
the corticomedial nuclear group of the amygdala projects to the [...]
hypothalamus, septum (feeding, repro)
31
the central nucleus of the amygdala projects to the [...]
hypothalamus, brainstem (autonomic regulation)
32
the basolateral nuclear group of the amygdala projects to the [...]
executive centers (decision making)
33
the "hyperfast" system of thinking uses the
amygdala | (Bypasses OFC and DLFC)
34
pathway of mesolimbic system
ventral tegmental area --> nucleus accumbens --> orbitofrontal cortex
35
what limbic system is the "want" pathway, involved in addiction and schizophrenia?
mesolimbic
36
receives sensory information, evaluates it for emotional content, and coordinates the response
amygdala
37
sensory information enters memory circuits through the [...] cortex which projects to the hippocampus
entorhinal
38
dentate gyrus and hippocampus are part of the [...] circuits
memory
39
central nucleus of the hypothalamus projects to the [...] to initiate fight or flight
intermediolateral cell column
40
entorhinal cortex is involved in [...] formation
memory
41
dorsal motor nucleus is involved in [...] function
parasympathetic
42
nucleus [...] controls speech and swallowing
nucleus ambigous
43
parts of the limbic circuit involved in creating memories [4]
dentate entorhinal cortex anterior nucleus of the thalamus mammillary bodies
44
organized into 5 major classes
tastants
45
taste receptor cells are innervated by [...] cells
ganglion
46
directly transmit action potentials to the olfactory bulb
primary olfactory neurons
47
sensory epithelia for both taste and gustation contain [...] cells, which can differentiate into new sensory cells
basal
48
these neurons are particularly sensitive to anoxia, which may lead to transient amnestic syndrome
pyramidal cells in the hippocampus
49
dopaminergic projections from the [...] to the [...] are part of the "want" pathway
dopaminergic projections from the [midbrain] to the [limbic system] are part of the "want" pathway
50
recognizes the emotional significance of objects/situations and determines their "emotional valence"
amygdala
51
stimulation of the "want" pathway plays a major role in [2]
addiction substance abuse
52
describe the "want" pathway
dopaminergic neurons in the midbrain ventral tegmentum project to limbic structures in the orbital frontal cortex
53
main causes of anosmia [4]
cocaine methotrexate thiamine deficiency COVID-19