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BMB Test 4 > B7-080 Substance Use Disorder > Flashcards

B7-080 Substance Use Disorder Flashcards

(79 cards)

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1
Q

diagnosis of substance use disorder requires symptoms in what general categories [4]

A

impaired control
physical dependence
social problems
risky use of substance

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2
Q

[…] symptom of substance use disorder indicates the individual is at risk

A

one

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3
Q

[…] symptoms indicate mild substance use disorder

A

2-3

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4
Q

[…] symptoms indicate moderate substance use disorder

A

4-5

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5
Q

[…] symptoms indicate severe substance use disorder

A

6+

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6
Q

therapy based upon principles of operant conditioning

A

contingency management

(often CM is added to another SUD treatment)

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7
Q

community reinforcement approach plus vouchers is an example of what type of therapy?

A

contingency management

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8
Q

the matrix model is helpful for individuals with […] SUD

A

stimulants

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9
Q

the matrix model is an example of […] therapy

A

behavioral

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10
Q

12 step facilitation therapy is an example of […] therapy

A

behavioral

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11
Q

Medication Assisted Treatment (MAT) is used for […] use disorder

A

opioid

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12
Q

OUD medications [3]

A

methadone
buprenorphine
naltrexone

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13
Q

OUD medication that is a full mu receptor agonist

A

methadone

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14
Q

OUD medication that is partial mu receptor agonist

A

buprenorphine

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15
Q

OUD medication that is mu receptor antagonist

A

naltrexone

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16
Q

has a very high affinity for mu receptors, so can out-compete other substances for binding

limits possibility of overdose [2]

A

buprenorphine
naltrexone

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17
Q

precautions of methadone [2]

A

prolonged QT
fatal overdose

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18
Q

common side effects of methadone [3]

A

sweating
constipation
respiratory depression

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19
Q

therapeutic dosage of methadone in adults

A

80-120 mg

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20
Q

precautions of buprenorphine [2]

A

withdrawal symptoms if taken too soon after an opioid
hepatitis

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21
Q

common side effects of buprenorphine [3]

A

nausea/vomiting
dizziness
constipation

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22
Q

can be administered via sublingually, orally, subq, subdermal implant, or transdermal patch

A

buprenorphine

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23
Q

common side effects of naltrexone [4]

A

nausea/vomiting
somnolence
injection side reaction
elevated liver enzymes

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24
Q

the patient must be opioid free for […] prior to using injectable naltrexone

A

7-10 days

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25
precautions to naltrexone [2]
withdrawal if currently taking opioids routine liver function monitoring
26
available orally or in IM monthly injections
naltrexone
27
depot injections are generally preferred for long term treatment, but what is a consideration?
naltrexone/buprenorphine cause withdrawal symptoms when taken concurrently with opioids
28
why do patients who were incarcerated have an increased risk of overdose after leaving the detention center?
naltrexone causes resensitization of mu receptors, so their previous usual dose is much more dangerous
29
rescue medication to prevent opioid overdose
naloxone
30
physicians must complete training to waiver to prescribe and dispence
buprenorphine (under the Drug Addiction Treatment Act)
31
therapy that helps patients develop critical skills that support long-term abstinence such as recognizing and avoid the situation in which they are most likely to use
CBT
32
therapy that uses a prize-based system that rewards patients who abstain
contingency management therapy
33
addresses the impact of drug use patterns on familial relationships and improves overall family functioning
family therapy
34
therapy that addresses patient readiness for change and helps resolve ambivalence toward drug treatment/use
motivational enhancement therapy
35
a breakdown of intention to limit consumption in a particular situation
impaired control
36
biological adaptation to persistent drugs in the body
physical dependence
37
drug use in particularly hazardous settings
risky use
38
role failures impacting family and societal functioning
social problems
39
adaptive changes in the [...] as a result of repeated intoxication/withdrawal cycles lead to reward deficit syndrome, increased stress reactivity and emotional dysregulation
amygdala
40
the [...] part of the brain is involved in drug reward
nucleus accumbens
41
modes of administration that maximize [...] are most reinforcing
rate of onset IV> smoked > snorted > orally injested
42
Substance is taken in larger amounts or over a longer period than was intended is a symptom of
impaired control
43
tolerance or withdrawal are symptoms of
physical dependence
44
There is a persistent desire or unsuccessful efforts to cut down or control substance use is a symptom of...
impaired control
45
A great deal of time is spent in activities necessary to obtain, use or recover from the effects of a substance is a symptom of...
impaired control
46
craving or a strong desire or urge to use the substance is a symptom of...
impaired control
47
Recurrent substance use resulting in a failure to fulfill major role obligations at work, school or home is a symptom of...
social problems
48
Continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance is a symptom of...
social problems
49
Important social, occupational, or recreational activities are given up or reduced because of substance use is a symptom of...
social problems
50
Recurrent substance use in situations in which it is physically hazardous is a symptom of...
risky use`
51
Substance use is continued despite knowledge of persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance is a symptom of...
risky use
52
The partial agoinist character of buprenorphine can elicit [...] symptoms
withdrawal
53
the most successful approach to increase adherance to treatment and reduce illicit opioid use
Opioid agonists combined with psychosocial treatments
54
Individuals initiating OUD treatment with either [....] had better clinical and cost outcomes in several areas than those beginning their OUD treatment via an alternative care pathway
buprenorphine or methadone
55
The core principles of [...] programs are acceptance, surrender and participation in the activities through peer-based meetings
12 step
56
therapy that centers around identifying triggers and avoiding risky situations
CBT
57
an incentive-based program based on operant principles
contingency management therapy
58
therapy that addresses ambivalence about recovery
motivational therapy
59
must be administered at certified Addiction Treatment Centers
methadone
60
requires specialized training to initiate therapy and avoid precipitated withdrawal
buprenorphine
61
The symptoms of preoccupation and anticipation of drug use reflect adaptive changes in which brain regions?
anterior cingulate, prefrontal cortex
62
brain structures guiding incentive salience
nucleus accumbens and thalamic nucleus
63
therapy particularly beneficial to address behavioral issues with young people and re-direct risky behaviors
family therapy
64
reverses monoamine and vesicular transporters leading to greater dopamine efflux
methamphetamine
65
factor that most predicts increased severity and poor clinical course of SUD
early use
66
increases the risk of developing SUDs by 2 to 4 times but it is not a predetermined outcome
family history (Children of parents with SUD are still more likely NOT to develop an SUD than to develop one)
67
accounts for about 60% of the risk for developing SUD but does not predict the severity or course of illness
genetics
68
explores the positive and negative consequences of continued drug use and incorporates self-monitoring techniques to identifiy situations that increase risk for use and helps develop strategies to cope with cravings and avoid high-risk situations
CBT
69
therapy that specifically addresses cue-induced relapse
CBT
70
commonly incorporated into the film with buprenorphine to prevent melting/injecting drug
naloxone (due to poor oral availability)
71
naloxone has [...] oral availability
poor
72
naltrexone has [...] oral availability
good
73
withdrawal symptoms are the result of
physiological dependence
74
reduces cravings and prevents withdrawal, but with a limited ceiling of effects thereby reducing the risk of fatal overdose
buprenorphine
75
methadone has [...] potential for fatal overdose
full
76
buprenorphine has [...] potential for fatal overdose
limited
77
what factor limits the use of buprenorphine?
severe physical dependence
78
integrated treatment plan incorporating pain management with motivational counseling to encourage adherence to treatment and monitoring
matrix model
79
patients with long history of SUD abuse have likely failed other therapies, so [...] is used
matrix model

BMB Test 4 (14 decks)

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