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PBD FINAL > Bacteria V > Flashcards

Bacteria V Flashcards

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1
Q

trench fever

A

bartonella qunitana

-lice spread

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2
Q

fever, headache, backache, rash, leg pain, relapses

A

trench fever

-bartonella quintana

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3
Q

cat scratch fever

A

bartonella henselae
-fever and malaise

bacillary angiomatosis

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4
Q

bacillary angiomatosis

A

proliferation of small vessels in skin of AIDS patients

  • with bartonella henselae
  • cat scratch fever
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5
Q

Q fever

A

coxiella burnetti

  • fever, sweats, pneumonia
  • NO rash
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6
Q

fever, sweats, pneumonia - NO rash

A

Q fever - coxiella burnetti

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7
Q

human ehrlichiosis

A

like rocky mtn spotted but no rash

-from tick bite

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8
Q

gram - corkscrew

A

spirochetes

-treponema, leptosira, borrelia

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9
Q

syphilis

A

treponema pallidum

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10
Q

stages of syphilis

A

primary - painless chancre
secondary - bacteremia and rash palms, soles, oral cavity and condyloma latum (wart like lesions)
latent - asymptomatic
tertiary - 6-40 years later - gummas, cardio sx, neurosyphilis

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11
Q

neurosyphilis

A

in tertiary stage

  • subacute meningitis
  • meningovascular
  • tabes dorsalis - ataxia, lose DTRs
  • general paresis - psychosis
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12
Q

arsyll robertson pupil

A

constricts during accomodation, not with light

in syphilis

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13
Q

saddle nose, saber shins, mulberry molars, teeth

A

congenital syphilis

-late stage

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14
Q

congenital syphilis

A

early - infected pregnant woman, rash, condyloma latum, runny nose

late - saddle nose, saber shins, molars and teeth, 8th nerve deafness

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15
Q

diagnosis of syphilis

A

darkfield microscopy

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16
Q

VDRL and RPR tests

A

nonspecific - lipids released during syphilis infection

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17
Q

FTA-ABS test

A

specific - for treponema infection - syphilis

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18
Q

syphilis rules of 6’s

A 
6 axial filaments
6 week intubation
6 weeks to heal ulcer
6 weeks to secondary
66% latent resolves
6 years to tertiary
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19
Q

jarish herxhemier phenomenon

A

worsening of symptoms with start of antibiotics

-release of pyrogen

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20
Q

treponema pallidum endemicum

A

endemic syphilis (bejel)

  • africa middle east
  • skin ulcers with gummas
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21
Q

treponema pallidum pertenue

A

yaws

  • moist tropics
  • gangosa - face disfigurement
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22
Q

yaws

A

gangosa - face disfigurement

-treponema pallidum pertenue

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23
Q

bejel

A

endemic syphilis

  • treponema pallidum endemicum
  • africa and middle east
  • skin ulcers with gummas
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24
Q

pinta

A

treponema pallidum cardeum

latin america
-red lesion > blue > white

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25
treponema pallidum cardeum
latin america - pinta - red lesion > blue > white
26
lyme disease
borrelia burgdorferi - number one cause of tick-borne illnes in US - ixodes tick
27
stahes of lyme disease
early localized - erythema chronicum migrans - spreads from bite site early disseminated - skin, NS, heart, joints, lesions on body, CN palsies, peripheral neuropathy, cardiac abnormalities late - chronic arthritis
28
relapsing fever
borrelia recurrentitis - fever, chills, HA, muscle aches - resolve 3-6 days - relapse after 8 days relapse - antigen variation
29
long thin spirochetes
leptospira
30
weils disease
renal failure, hepatic jaundice, altered LOC | -leptospira interrogena interohemorrhagic
31
leptospira interrogans
2 phases - 1 - leptospiremic - fever, HA, malaise, muscle aches - 2 - immune - meningisums, WBCs in CSF, IgM antibodies
32
acid fast
mycobacterium
33
acid fast stain
resist decolorization with alcohol - hold fast to red stain - not acid fast - lost red take on blue 1 - carbolfuschin - red, heated 2 - acid alcohol 3 - couterstain methylene blue lipids - don't dissolve when alcohol applied - red stays
34
tuberculosis
mycobacterium tuberculosis
35
lipid in acid fast organisms
mycolic acid
36
cord factor
mycoside formed by union by 2 mycolic acids and disaccharide
37
sulfatides
like cord factor - with sulfates
38
wax D
mycoside adjuvant
39
TB path
1 - local infiltrate of neutros and M0s -phagocytosed bacteria not killed 2 - local destruction and necrosis - caseous -soft caseous center, surrounded by M0s, multinucleated giant cells, fibroblasts, collagen deposits (granuloma)
40
PPD skin test
for TB - reveal whether or not person has been infected - considered to have latent TB
41
false positive PPD skin test
BCG (bacillus calmette guerin) vaccine for TB
42
false negative test
anergic individuals | -lack normal immune reponse
43
primary TB
inspired droplets - enter macrophages - walled off in caseous granulomas - fibrosis, calcification, scar formation - form tiny tubercles
44
ghon focus
calcified tubercle in middle or lower lung zone
45
symptomatic primary TB
children, elderly, immunocompromised - organisms not suppressed - enlarged mediastional or hilar nodes severe - holes in lungs form -become fluid filled
46
secondary TB
reactivation - often in AIDS patients - affect multiple organ systems: pulmonary - most commons - apical areas around clavicles -low grade fever, night sweats, weight loss, productive cough - pleural and pericardial infection - fluid around heart/lung - lymph node infection - cervical lymph noes - swell/mat together - scrofula - kidney - red and white blood cells in urine - no bacteria - skeletal - potts disease - destroys IV discs and bodies - CNS - granulomas and meningitis - miliary TB - tiny disseminated tubercles
47
scrofula
node TB infection
48
sterile pyuria
RBC and WBC in urine, but no bacteria on gram stain with TB -mycobacterium tuberculosis
49
Potts disease
destroyed IV discs and bodies with TB mycobacterium tuberculosis
50
diagnosis of active TB
acid fast stain of sputum
51
rule of 5s with TB
droplet nuclei 5 micrometers 5% risk of reacivation in first 2 years then 5% lifetime risk -HIV - 5+5% risk of reactivation each year
52
hansens disease
leprosy | -mycobacterium leprae
53
impossible to grow on artifical media - only on footpads
mycobacterium leprae
54
affects cooler areas of body
mycobacterium leprae | -skin, nerves, eyes, nose, testes
55
lepromatous leprosy
severest form (no cell mediated response) - skin lesions all over body - face skin thickened - leonine facies - saddlenose deformity - testicular damage - infertility - loss of sensation - glove and stocking distribution negative skin test
56
skin lesions all over body, face skin thickened, saddlenose deformity, testicular damage, blindness, glove and stocking loss of sensation
lepromatous leprosy
57
tuberculoid leprosy
can mount cell-mediated response -localized superficial unilateral skin and nerve involvement positive skin test
58
1 or 2 skin lesions -hypopigmented and elevated blotches, hairless, dimished sensation -enlarged nerve neark lesion
tuberculoid leprosy
59
mycobacterium avium complex
MAC - common in AIDS with T cells < 50 - unexplained fever, weight loss, diarrhea, malaise, elevation alkaline phosphatse
60
unexplained fever, weight loss, diarrhea, malaise, elevated alkaline phosphatase
mycobacterium avium complex
61
bacteria without cell walls
mycoplasm
62
mycoplasma pneumonia
bronchitis and pneumonia
63
number one cause of bacterial bronchitis and pneumonia in teenagers and young adults
mycoplasm pneumonia
64
gradual onset of fever, sore throat, malaise, persistent dry hacking cough, but don't feel had
walking pneumonia | -mycoplasm pneumonia
65
stevens-johnson syndrome
severe skin reaction with erythematous vesicles and bullae over mucocutaneous junctions of mouth, eyes, skin complication with mycoplasm pneumonia
66
cold agglutinins
mycoplasma pneumonia -IgM - against I antigen put blood in tube - put on ice - should clump -warm up - not clumped anymore
67
mycoplasm culture
fried egg appearance
68
ureaplasma urealyticium
mycoplasma T strain urea-lytic
69
urethritis in sexually active young women
ureaplasma urealyticium -metabolize urea into ammonia and CO2 -also, n. gonorrhea and c. trachomatis

PBD FINAL (10 decks)

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