bacterial and enviromental processes Flashcards
What are existing genetic factors
-chromosome
-plasmid
-mobile genetic elements (pathogenicity islands)
What does the two component system associate with
LPS (lipoploysacchiride) modification
What is the quorum sensing system associated with
Biofilm formation
What can the EnvZ system detect
Can sense changes in osmolarity facilitates survival of microbe
What type of signals induce environmental regulation
-environmental change
-signalling molecule
What type of sensors induce environmental regulation
-ligand binding (change protein conformation for protein-protein interactions)
What type of regulator induce environmental regulation
Specific DNA binding protein - binds in control region
What type of regulon induce environmental regulation
Group of genes controlled by a common regulator
What is a biofilm
Community of bacteria cells enclosed in a self-produced polymeric matrix
What is quorum sensing
Regulatory mechanism - cell population density dependant regulation mediated via self generated extra cellular signal molecules
What does quorum sensing have the ability to do
Activate and repress genes
What are the effects of biofilm usage
The bacteria is able to hide as the biofilm covers it however causes inflammation and harm to host
