Behavioral/toxicology/womd Flashcards

(75 cards)

1
Q

What is the most common cause of carbon monoxide exposure?

A

Incomplete combustion of fossil fuels.

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2
Q

What is the hallmark symptom of carbon monoxide poisoning?

A

Headache.

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3
Q

How does cyanide poisoning affect cells?

A

Blocks cytochrome oxidase; prevents cellular oxygen use.

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4
Q

What are SLUDGE symptoms in organophosphate poisoning?

A

Salivation, Lacrimation, Urination, Defecation, GI upset, Emesis.

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5
Q

What is the antidote for organophosphate poisoning?

A

Atropine and pralidoxime (2-PAM).

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6
Q

What receptor type is blocked in anticholinergic poisoning?

A

Muscarinic and nicotinic acetylcholine receptors.

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7
Q

Name two common anticholinergic drugs.

A

Benadryl and Atrovent.

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8
Q

What are hallmark signs of anticholinergic toxicity?

A

Hot, dry skin, mydriasis, tachycardia, delirium.

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9
Q

What does COMEBIG stand for in toxicology treatment?

A

Charcoal, Oxygen, Monitor, ECG, B/P, IV access, Glucose check.

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10
Q

What is the antidote for TCA overdose?

A

Sodium Bicarbonate.

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11
Q

What toxidrome presents with miosis, bradycardia, and bronchorrhea?

A

Cholinergic toxidrome.

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12
Q

What is the treatment for cyanide poisoning?

A

Hydroxocobalamin or sodium thiosulfate.

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13
Q

What is the most common symptom of salicylate toxicity?

A

Tinnitus.

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14
Q

What acid-base disturbance is caused by aspirin overdose?

A

Mixed respiratory alkalosis and metabolic acidosis.

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15
Q

What is the antidote for acetaminophen overdose?

A

N-acetylcysteine (NAC).

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16
Q

What lab test helps assess acetaminophen toxicity risk?

A

Rumack-Matthew Nomogram.

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17
Q

What is the triad for opioid overdose?

A

CNS depression, respiratory depression, pinpoint pupils.

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18
Q

What is the antidote for opioid overdose?

A

Naloxone.

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19
Q

What is the primary danger in beta-blocker overdose?

A

Bradycardia and hypotension.

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20
Q

What is used to treat beta-blocker overdose?

A

Glucagon.

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21
Q

What electrolyte imbalance may be seen in digoxin toxicity?

A

Hyperkalemia.

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22
Q

What visual symptom is unique to digoxin toxicity?

A

Yellow or green vision (xanthopsia).

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23
Q

What is the antidote for digoxin toxicity?

A

Mag

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24
Q

What is the main risk with calcium channel blocker overdose?

A

Hypotension and bradycardia.

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25
What is used to treat calcium channel blocker overdose?
Calcium chloride or calcium gluconate.
26
What is the primary symptom of methanol poisoning?
Visual disturbances ("snowfield vision").
27
What is the antidote for methanol and ethylene glycol poisoning?
Fomepizole or ethanol.
28
What metabolic issue is caused by methanol toxicity?
High anion gap metabolic acidosis.
29
What does MUDPILES stand for?
Causes of anion gap metabolic acidosis.
30
What household product is associated with methanol poisoning?
Windshield washer fluid.
31
What is the most common cause of pesticide poisoning?
Organophosphates.
32
What class of drugs cause anticholinergic toxidrome?
Antihistamines, tricyclics, atropine, antipsychotics.
33
What is the treatment for anticholinergic toxidrome?
Benzodiazepines and supportive care.
34
What is the danger of giving physostigmine in TCA overdose?
It may induce seizures or asystole.
35
What is the first step in managing a suspected toxic ingestion?
Airway, breathing, and circulation (ABCs).
36
What is whole bowel irrigation used for?
Ingestion of sustained-release or iron tablets.
37
What color is vomit in iron overdose?
Green or black.
38
What is the antidote for iron toxicity?
Deferoxamine.
39
What does a "cherry red" skin color indicate?
Carbon monoxide or cyanide poisoning.
40
What imaging is used to detect ingested metals or tablets?
Abdominal X-ray.
41
What class of drugs causes serotonin syndrome?
SSRIs, MAOIs, SNRIs, TCAs.
42
What are symptoms of serotonin syndrome?
Hyperreflexia, clonus, agitation, hyperthermia.
43
What is the treatment for serotonin syndrome?
Benzodiazepines, cooling, and cyproheptadine.
44
What substance causes metabolic acidosis with calcium oxalate crystals?
Ethylene glycol.
45
What is the antidote for ethylene glycol poisoning?
Fomepizole or ethanol.
46
What cardiac drug causes blue vision?
Sildenafil (Viagra).
47
What drug causes lactic acidosis and GI upset in overdose?
Metformin.
48
What syndrome presents with lead lines on gums and basophilic stippling?
Lead poisoning.
49
What is the antidote for lead poisoning?
EDTA or dimercaprol.
50
What symptoms occur in lithium toxicity?
Tremor, ataxia, confusion, seizures.
51
What is the treatment for lithium overdose?
IV fluids and possibly dialysis.
52
What is the risk of isoniazid (INH) overdose?
Seizures and lactic acidosis.
53
What is the antidote for INH toxicity?
Pyridoxine (Vitamin B6).
54
What over-the-counter drugs can cause kidney damage in overdose?
NSAIDs like ibuprofen.
55
What is a toxidrome?
A group of signs and symptoms characteristic of a toxin.
56
What are the 4 classic toxidromes?
Cholinergic, anticholinergic, opioid, and sympathomimetic.
57
What drug class causes dilated pupils, sweating, and agitation?
Sympathomimetics.
58
What is the antidote for benzodiazepine overdose?
Flumazenil (use with caution).
59
What substance causes delayed hepatic necrosis?
Acetaminophen.
60
What are the stages of acetaminophen poisoning?
GI upset → latent → hepatic injury → recovery or failure.
61
What is a hallmark of arsenic poisoning?
Garlic odor on breath.
62
What is the antidote for arsenic and mercury poisoning?
Dimercaprol (BAL).
63
What poison is commonly found in old paints?
Lead.
64
What medication reverses methotrexate toxicity?
Leucovorin.
65
What medication can cause methemoglobinemia?
Benzocaine.
66
What is the antidote for methemoglobinemia?
Methylene blue.
67
What is the first priority in any poisoning?
Stabilize the patient (ABCs).
68
What type of poisoning presents with bitter almond odor?
Cyanide.
69
What substance is associated with "Monday morning headache"?
Nitroglycerin or organic nitrates.
70
What are the key symptoms of hydrocarbon ingestion?
Cough, dyspnea, chemical pneumonitis.
71
What is the treatment for hydrocarbon ingestion?
Supportive care, avoid emetics or lavage.
72
What substance is toxic in small doses and used in chemotherapy?
Colchicine.
73
What is a classic sign of barbiturate overdose?
Respiratory depression.
74
What is the antidote for warfarin toxicity?
Vitamin K.
75
What over-the-counter medication can cause salicylate toxicity?
Aspirin.