Flashcards in Biliary Secretion Deck (12):
Canines have what kind of gallbladder?
Felines have what kind of gallbladder?
double gallbladder (sometimes single)
Explain the difference in biliary ductal anatomy between canine and feline
canine: separate bile duct and pancreatic duct
feline: bile duct and pancreatic duct merge to form common bile duct
Name the 4 anatomic units of biliary secretion
What is the composition of bile salts?
Name the 3 functions of biliary secretion
1. excretory route of drugs and metabolites
2. HCO3 for acid neutralization
3. bile salts for fat digestion and absorption
Name the 4 components that regulate biliary secretion
cholecystokinin (gallbladder, sphincter of Oddi)
secretin (bile duct)
bile salts (bile duct)
What is bile acid?
steroid 4-ring structure with hydroxyl groups
changes from: cholic acid - deoxycholic acid - lithocholic acid
How do cats conjugate bile acid?
cats are obligate taurine conjugators
How do dogs conjugate bile acid?
dogs primarily conjugate with taurine but can also use glycine
Name the 2 ways that bile salts digest and absorb fat