Biliary Secretion Flashcards Preview

Physiology (Gastrointestinal) > Biliary Secretion > Flashcards

Flashcards in Biliary Secretion Deck (12):
1

Canines have what kind of gallbladder?

single gallbladder

2

Felines have what kind of gallbladder?

double gallbladder (sometimes single)

3

Explain the difference in biliary ductal anatomy between canine and feline

canine: separate bile duct and pancreatic duct
feline: bile duct and pancreatic duct merge to form common bile duct

4

Name the 4 anatomic units of biliary secretion

hepatocytes
canaliculi
ductules
ducts

5

What is the composition of bile salts?

bile salts
water
electrolytes
cholesterol
phospholipids
bilirubin
hormones
protein

6

Name the 3 functions of biliary secretion

1. excretory route of drugs and metabolites
2. HCO3 for acid neutralization
3. bile salts for fat digestion and absorption

7

Name the 4 components that regulate biliary secretion

acetylcholine (gallbladder)
cholecystokinin (gallbladder, sphincter of Oddi)
secretin (bile duct)
bile salts (bile duct)

8

What is bile acid?

steroid 4-ring structure with hydroxyl groups

changes from: cholic acid - deoxycholic acid - lithocholic acid

9

How do cats conjugate bile acid?

cats are obligate taurine conjugators

10

How do dogs conjugate bile acid?

dogs primarily conjugate with taurine but can also use glycine

11

Name the 2 ways that bile salts digest and absorb fat

emulsification
micellarization

12

Explain enterohepatic re-circulation of bile salts

bile salts are reabsorbed by a specialized mucosa in the terminal ileum
bile salts are carried in portal venous blood to liver