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Physiology (Gastrointestinal) > Gastrointestinal Blood Flow > Flashcards

Flashcards in Gastrointestinal Blood Flow Deck (18):
1

Name some characteristics of the regional gastrointestinal circulation

splanchnic circulation = GI tract + spleen
25% of cardiac output perfuses gut
sub-serves motility, secretion, digestion, absorption
storage site for mobilization of blood during exercise
overlap in submucosal arteries preserves arterial flow

2

The celiac artery perfuses what part of the GI tract?

liver
stomach spleen
pancreas

3

The superior mesenteric artery perfuses what part of the GI tract?

pancreas
small intestine
colon

4

The inferior mesenteric artery perfuses what part of the GI tract?

colon

5

What are the mammalian portal venous systems?

hepatic
hypophyseal
islet-acinar

6

What are the 2 most important regulators of blood flow to the GI tract?

autonomic nerves
general hemodynamics

7

What are the effects of autonomic nerves on blood flow to the GI tract?

sympathetic - vasodilation
parasympathetic - increased blood flow in secretory organs, decreased blood flow in smooth muscle
intrinsic - VIP mediated vasodilatation

8

What are the general hemodynamic effects on blood flow to the GI tract?

decreased cardiac output
decreased arterial pressure
decreased blood volume
decreased fluidity of blood

9

What is ischemia?

when blood flow is insufficient to deliver an amount of oxygen and nutrients necessary for maintenance or cell integrity

10

What is reperfusion?

occurs when blood flow is restored to ischemic tissue

11

What is IR injury?

cellular injury resulting from a period of ischemia followed by restoration of blood flow to ischemic tissue

12

Explain occlusive ischemia

direct disruption of gastrointestinal blood flow such as strangulation, volvulus, intussusception, or thromboembolism

13

Explain non-occlusive ischemia

results from systemic conditions such as sepsis

14

What are the risk factors for gastric dilitation/volvulus?

large and giant breeds
increasing age
rapid food consumption
one meal per day

15

What are the principles of management of gastric dilitation/volvulus?

shock management
gastric decompression
surgery

16

What is associated with intussusception?

parasitism
foreign bodies
viral enteritis
lymphoma

17

What is the therapy for intussusception?

reduction or resection

18

Name some signs of porta-caval shunting

small liver volume
cachexia
small body size
failure to grow
anemia
microcytosis