BIO 205 PROTEIN STRUCTURE

Question 1

polypeptides are

Answer 1

chains of amino acids linked by peptide bonds

Question 2

amino acid formula

Answer 2

H
             |
H2N -- C -- COOH
             |
            R

R= side-chain group

Question 3

unique R groups defining..

Answer 3

specific amino acids

Question 4

amino acid at pH 7

Answer 4

H
                  |
(+) H3N -- C -- COO (-)
                  |
                 R

Question 5

formation of a polypeptide via peptide bond

Answer 5

pics

Question 6

condensation of 2 amino acids == dipeptide

Answer 6

together by amide linkage

- remove 1 water molecule

Question 7

Polar amino acids - Hydrophilic/Hydrophobic

Answer 7

Hydrophilic

Question 8

NonPolar amino acids - Hydrophilic/Hydrophobic

Answer 8

Hydrophobic

Question 9

Asparatic acid

Answer 9

[Asp]
acidic
neg polar, hydrophilic

Question 10

Glutamic acid

Answer 10

[Glu]
acidic
neg polar, hydrophilic

Question 11

Arganine

Answer 11

[Arg]
basic
pos polar, hydrophilic

Question 12

Lysine

Answer 12

[Lys]
basic
pos polar, hydrophilic

Question 13

Histidine

Answer 13

[His]
basic
pos polar, hydrophilic

Question 14

Asparagine

Answer 14

[Asn]

uncharged polar, hydrophilic

Question 15

Glutamine

Answer 15

[Glu]

uncharged polar, hydrophilic

Question 16

Serine

Answer 16

[Ser]

uncharged polar, hydrophilic

Question 17

Threonine

Answer 17

[Thr]

uncharged polar, hydrophilic

Question 18

Tyrosine

Answer 18

[Tyr]

uncharged polar, hydrophilic

Question 19

Alanine

Answer 19

[Ala]

non polar, hydrophobic

Question 20

Glycine

Answer 20

[Gly]
non polar, hydrophobic
SMALLEST ; only H

Question 21

Valine

Answer 21

[Val]

non polar, hydrophobic

Question 22

Leucine

Answer 22

[Leu]

non polar, hydrophobic

Question 23

Isoleucine

Answer 23

[Ile]

non polar, hydrophobic

Question 24

Proline

Answer 24

[Pro]

non polar, hydrophobic

Question 25

Phenylalanine

Answer 25

[Phe] | non polar, hydrophobic

Question 26

Methionine

Answer 26

[Met] | non polar, hydrophobic

Question 27

Tryptophan

Answer 27

[Trp] | non polar, hydrophobic

Question 28

Cysteine

Answer 28

[Cys] | non polar, hydrophobic

Question 29

unfolded protein

Answer 29

- disordered, high entropy | - few non covalent (enthalpies) interactions

Question 30

folded protein

Answer 30

- highly ordered, low entropy | - many non covalent interactions

Question 31

forces that determine protein folding into its native 3-D structure

Answer 31

- covalent bonding - hydrogen bonding - van der waals - hydrophobic effects