Biochemical events in Dental Plaque Flashcards Preview

BDS 2: Adult Restorative > Biochemical events in Dental Plaque > Flashcards

Flashcards in Biochemical events in Dental Plaque Deck (22)
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1

Ultimately what causes caries?

Bacteria

2

How would you describe the structure of dental plaque?

Highly organised structure

3

What is the water and solid composition of dental plaque?

- 80% water
- 20% solid

4

20% of plaque composition is solid. What is this 'solid' made up from?

Give the compositions of these.

- 50% Bacterial and salivary proteins
- 25% Carbohydrates and lipids
- 25% Inorganic components

5

What are the carbohydrates and lipids in the dental plaque synthesised from?

Synthesised by the bacteria in the plaque

6

What is plaque fluid?

Extracellular aqueous phase of dental plaque

7

In nL how much plaque fluid can be found in a 500 μg wet weight plaque sample?

150 nL

8

What can changes in ionic composition of plaque fluid lead to?

Cariogenic conditions

9

What is rested plaque fluid?

Plaque fluid one to several hours after eating

10

What is starved plaque fluid?

Plaque fluid following overnight fasting

11

Which plaque fluid contains more amino acids? Rested or Starved?

Rested plaque fluid

12

Which plaque fluid is more acidic? Rested or Starved?

Rested plaque fluid

13

What is the main acid involved in caries formation?

Lactic acid

14

What contributes to the extent of pH drop after glucose challenge? (5)

- Type and amount of sugars available
- Bacteria present
- Salivary composition and flow
- Other food ingested
- Thickness and age of dental plaque

15

What is the resting plaque pH of a caries-inactive patient?

Compare this to a patient that is caries-prone

Resting pH roughly 6.5 - 7

Caries-prone has a lower resting pH

16

What affects the metabolic properties of plaque?

Bacterial composition affects metabolic properties of plaque

17

Which type of sugars cause the most dental caries?

Small sugars such as monosaccharides

18

What are the 3 'fates' of pyruvate?

- Ethanol
- Lactic acid
- Further oxidation to return to citric acid cycle

19

What determines the fate of pyruvate?

The different types of bacteria

20

List some cariogenic bacteria (3)

- Streptococci
- Actinomyces
- Lactobacilli spp

21

Define Acidogenicity

The ability to produce acid rapidly from fermentable carbohydrate

22

Define Aciduricity

The ability to survive and continue to produce acid at acidic pH