Biochemisty Flashcards

(40 cards)

1
Q

What is the primary function of the Pentose Phosphate Pathway (PPP)?

A

To generate NADPH and ribose-5-phosphate for nucleotide synthesis.

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2
Q

True or False: The Pentose Phosphate Pathway occurs in the mitochondria.

A

False. It occurs in the cytoplasm.

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3
Q

Fill in the blank: Glutathione Reductase is an enzyme that helps maintain the _______ state of glutathione.

A

reduced

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4
Q

What are the two main phases of the Pentose Phosphate Pathway?

A

Oxidative and non-oxidative phases.

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5
Q

Which molecule is a key product of the oxidative phase of the PPP?

A

NADPH

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6
Q

What is the role of glutathione in the body?

A

It acts as an antioxidant, protecting cells from oxidative damage.

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7
Q

In a fed state, insulin levels are _______.

A

elevated

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8
Q

What is the effect of glucagon in the fasted state?

A

It promotes gluconeogenesis and glycogenolysis.

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9
Q

Which vitamin is essential for folate metabolism?

A

Vitamin B12

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10
Q

True or False: Folate is necessary for DNA synthesis.

A

True.

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11
Q

What is the main carbohydrate source during the fasted state?

A

Glucose from gluconeogenesis.

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12
Q

Fill in the blank: The non-oxidative phase of the PPP produces sugars that can be converted into _______.

A

glycolytic intermediates

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13
Q

Which enzyme is responsible for converting oxidized glutathione to reduced glutathione?

A

Glutathione reductase

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14
Q

What is the primary energy source for tissues during the fed state?

A

Glucose

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15
Q

True or False: In the fasted state, the body primarily relies on fat for energy.

A

True.

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16
Q

What is one consequence of folate deficiency?

A

Megaloblastic anemia

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17
Q

Which pathway is activated by high levels of NADP+?

A

The Pentose Phosphate Pathway.

18
Q

What is the role of ribose-5-phosphate in the cell?

A

It is a precursor for nucleotide synthesis.

19
Q

In terms of metabolism, what does the term ‘fed state’ refer to?

A

The period after eating when nutrients are being absorbed.

20
Q

What is the impact of insulin on glucose uptake in the fed state?

A

Insulin promotes glucose uptake by tissues.

21
Q

What is the primary molecule that cells use for energy?

A

Adenosine triphosphate (ATP)

22
Q

True or False: Glycolysis occurs in the mitochondria.

23
Q

Fill in the blank: The process of converting glucose into pyruvate is called ______.

24
Q

What are the end products of glycolysis?

A

2 pyruvate, 2 ATP, and 2 NADH

25
Which cycle is primarily responsible for the oxidation of acetyl-CoA?
Krebs cycle (Citric Acid Cycle)
26
Multiple Choice: Which of the following is not a product of the Krebs cycle? A) CO2 B) ATP C) Glucose D) NADH
C) Glucose
27
What is the role of NAD+ in cellular respiration?
It acts as an electron carrier.
28
True or False: The electron transport chain is located in the cytoplasm.
False
29
What is the main function of the electron transport chain?
To generate ATP through oxidative phosphorylation.
30
Fill in the blank: The end product of the electron transport chain is ______.
water
31
What type of metabolism breaks down molecules to produce energy?
Catabolism
32
Multiple Choice: Which of the following is a type of anaerobic respiration? A) Lactic acid fermentation B) Krebs cycle C) Glycolysis D) Oxidative phosphorylation
A) Lactic acid fermentation
33
True or False: Photosynthesis and cellular respiration are completely independent processes.
False
34
What is the primary purpose of the pentose phosphate pathway?
To generate NADPH and ribose-5-phosphate.
35
Fill in the blank: The energy investment phase of glycolysis uses ______ ATP.
2
36
What is the term for the totality of metabolic processes in a cell?
Metabolism
37
Multiple Choice: Which molecule is produced during the transition reaction before entering the Krebs cycle? A) Acetyl-CoA B) Pyruvate C) Glucose D) NAD+
A) Acetyl-CoA
38
True or False: The Krebs cycle occurs twice for each glucose molecule that is fully oxidized.
True
39
What is the main product of fermentation in yeast?
Ethanol
40
Fill in the blank: The final electron acceptor in aerobic respiration is ______.
oxygen