Biochemisty Flashcards
(40 cards)
What is the primary function of the Pentose Phosphate Pathway (PPP)?
To generate NADPH and ribose-5-phosphate for nucleotide synthesis.
True or False: The Pentose Phosphate Pathway occurs in the mitochondria.
False. It occurs in the cytoplasm.
Fill in the blank: Glutathione Reductase is an enzyme that helps maintain the _______ state of glutathione.
reduced
What are the two main phases of the Pentose Phosphate Pathway?
Oxidative and non-oxidative phases.
Which molecule is a key product of the oxidative phase of the PPP?
NADPH
What is the role of glutathione in the body?
It acts as an antioxidant, protecting cells from oxidative damage.
In a fed state, insulin levels are _______.
elevated
What is the effect of glucagon in the fasted state?
It promotes gluconeogenesis and glycogenolysis.
Which vitamin is essential for folate metabolism?
Vitamin B12
True or False: Folate is necessary for DNA synthesis.
True.
What is the main carbohydrate source during the fasted state?
Glucose from gluconeogenesis.
Fill in the blank: The non-oxidative phase of the PPP produces sugars that can be converted into _______.
glycolytic intermediates
Which enzyme is responsible for converting oxidized glutathione to reduced glutathione?
Glutathione reductase
What is the primary energy source for tissues during the fed state?
Glucose
True or False: In the fasted state, the body primarily relies on fat for energy.
True.
What is one consequence of folate deficiency?
Megaloblastic anemia
Which pathway is activated by high levels of NADP+?
The Pentose Phosphate Pathway.
What is the role of ribose-5-phosphate in the cell?
It is a precursor for nucleotide synthesis.
In terms of metabolism, what does the term ‘fed state’ refer to?
The period after eating when nutrients are being absorbed.
What is the impact of insulin on glucose uptake in the fed state?
Insulin promotes glucose uptake by tissues.
What is the primary molecule that cells use for energy?
Adenosine triphosphate (ATP)
True or False: Glycolysis occurs in the mitochondria.
False
Fill in the blank: The process of converting glucose into pyruvate is called ______.
glycolysis
What are the end products of glycolysis?
2 pyruvate, 2 ATP, and 2 NADH