biological approach to treating depression Flashcards
(5 cards)
What are the 3 drugs for the biological treatment of OCD
SSRIs
Tricyclics
Benzodiazepines (Anti-anxiety)
How do SSRIs work
Serotonin is released into a synapse from a neuron
It targets the receptors cells on the receiving neuron at receptor sites and afterwards is re-absorbed by the initial neuron sending the message
In order to increase the levels of serotonin at the synapses and increase stimulation to the receiving neuron this re-absorption (re-uptake) is inhibited
Increases levels of serotonin
This reduces anxiety and makes the patient feel more relaxed
How does Tricyclics work
Tricyclics block the transporter mechanism that re-absorbs serotonin and noradrenaline into the pre-synaptic cell after it has fired .
As a result more of these neurotransmitters are left in the synapse ,prolonging their activity and easing transmission of the next impulse which treats OCD
How do Benzodiazepines (BZ) work
BZ slow down the activity of CNS by enhancing the neurotransmitter GABA which is when that it’s released it has a general quietening effect on many of the neurons in the brain . It does this by reacting with GABA receptors on the outside of the receiving neuron.
When GABA locks into theses receptors it opens a channel that increases the flow of chlorine ions into the neuron . The chlorine ions makes it harder for the neuron to be stimulated by other neurotransmitters,thus slowing down its activity and making the person feel more relaxed which reduces anxiety