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Biosecurity Flashcards

(48 cards)

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1
Q

Goal of bio security/bio containment plan

A

prevent the transmission of infectious agents into
and among individuals, groups of animals, farms, or
regions

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2
Q

3 principles of bio security and bio containment

A

**epidemiologic triangle
– Increase host resistance
– Eliminate disease reservoirs
– Prevent/minimize transmission

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3
Q

Bio security plan: intrinsic and extrinsic elements

A

– Intrinsic: Immune status, nutrition, genetics
– Extrinsic: Movement pathways, segregation, physical barriers

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4
Q

Biosecurity plan depends on which principles (hint: there’s 7 principles)

A

HACCP= hazard analysis and critical control points

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5
Q

Between 1995 and 2005, number of dairy farms

A

Decreased by 44%

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6
Q

4 exposure pathways to dairy cattle

A

–Oral: Contaminated feed or water
• Inhalation - Dust & manure particles
• Physical – Oronasal cavities, teat ends, wounds
• Indirect – Fomites and Vectors

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7
Q

4 farm biosecurity risks

A

• Cattle from other premises – Ideally all should have complete health & vaccination records, New cattle should be isolated for 10 days – 3 weeks
• Feedstuffs – Commonly contaminated by manure, water or wildlife
• Vehicles and People
– Dairy farms are the hub of many logistical systems
– Restricting access is of paramount importance
– Even farm workers can be the source of contamination
• Drinking water
– Restrict wildlife access and perhaps filter or treat

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8
Q

Most common infectious diseases in dairy operations (7)

A

Bovine virus diarrhea
Brucellosis
Tuberculosis
Staph
Salmonella
Mycobacterium
Neospora

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9
Q

2 control methods for infectious diseases: dairy operations

A

Testing
Vaccination

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10
Q

Bio containment definition

A

-The result of actions to prevent the spread of
disease agents among groups of animals at a
facility or farm
-Serves as an important backup to biosecurity (When biosecurity is breached, biocontainment
lessens the damage)

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11
Q

Biosecurity definition

A

The result of management practices to avoid
(re)introduction of disease agents to a facility or
region (e.g., farm, veterinary hospital, nation)

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12
Q

New cattle entering farm should be isolated for how long

A

10 days-3 weeks

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13
Q

Bio containment maintenance methods (10)

A

-vaccination
-unidirectional flow of animals, people, material (separate 4 major animals groups)
-scheduled cleaning of facilities and equipment
-logical milking order (lowest to highest mastitis rates)
-move newborn calves to individual stalls immediately
-avoid direct contact between animal groups (don’t share food)
-limit exposure to recycled water
-proper manure handling

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14
Q

Bio containment maintenance: newborn calves

A

– Move to individual hutches/stalls immediately after birth
– 4 qts of colostrum w/in 24 hrs of birth
– No waste milk (normal milk or milk replacer) —> Unless Pasteurized
– Vaccinate 3-4 wks prior to movement to group pens

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15
Q

Bio containment maintenance: logical milking orde

A

– LOWEST MASTITIS RATE: First-lactation & recently calved cows
– High-producing cows
– Lower-producing cows
– HIGHEST MASTITIS RATE: Cows at the end of lactation period

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16
Q

Bio containment maintenance: separation into 4 major animals groups

A

Newborns
Young stock and heifers
Lactating cows
Non lactating cows

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17
Q

H5N2 spread: causes and biosecurity breaches

A

– Virus was introduced into US via wild bird migration
– Windborne detection of virus up to 1 km from source
– Equipment sharing among farms
– Lack of vehicle cleaning & disinfection
– Rodents and wild birds inside poultry barns
– Bird/poultry exhibits at State/county fairs

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18
Q

Importance of hospital precautions (examples)

A

-Monkey pox outbreak in 2003 —> 25% of infected people were vet personnel
-66% of vets report animal related injury resulting in lost work or hospitalization
-needle sticks are one of most frequent accidents

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19
Q

Common zoonoses in vet personnel (9)

A

Salmonellosis
Cryptosporidiosis
Plague
Sporotrichosis
MRSA
Avian chlamydiosis/psittacosis
Dermatophytosis
Leptospirosis
Q fever

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20
Q

Which precaution method gets the most emphasis

21
Q

PPE and actions (6)

Study These Flashcards
A

-wash hands
-use gloves and sleeves if infectious disease suspected
-facial protection
-use masks for respiratory tract protection
-protective outerwear
-animal related injury prevention (restraint, escape plans)

22
Q

Hand sanitizers should be what percent alcohol

23
Q

Protective actions during procedures

Study These Flashcards
A

-clean and safe patient intake
-exam animals
-infection, venipuncture (always use sharps container, use gloves, never remove caps with mouth)
-dentistry, bronchoscopy (aerosols require PPE)
-resuscitation (don’t blow into mouth of animal via endotracheal tube)
-obstetrics
-necropsy
-diagnostic specimen handling (no food or drink in lab)
-wound care may require PPE

24
Q

Environmental infection control

Study These Flashcards
A
  1. Cleaning & disinfection of equipment/surfaces
  2. Isolation of animals with IDs
  3. Laundry handling
  4. Decontamination & spill response
  5. Veterinary medical waste
  6. Rodent & vector control
25
Vaccination policy for employees (3)
Rabies Tetanus Influenza
26
Disease control definition
The reduction of disease incidence, prevalence, morbidity or mortality to a locally acceptable level as a result of deliberate efforts; continued intervention measures are required to maintain the reductionq
27
Disease control is combination of (3)
Initial intervention strategies • On-going disease control strategies • Monitoring and surveillance activities
28
Fibromuscular dysplasia early 1900s vs today: ranked disease control mechanisms
-early 1900s: do nothing, quarantine, slaughter/cull, control host movement, FOMITE CONTROL, CLEAN AND DISINFECT -today: control host movement, quarantine, slaughter/cull, fomite control, vaccination?
29
CDC definition of eradication
Permanent reduction to zero of the worldwide incidence of infection caused by a specific agent as a result of deliberate efforts; intervention measures are no longer needed
30
2 successful global eradication programs (diseases)
Smallpox in 1980 Rinderpest in 2011
31
Control and eradication options (4)
1. Animal depopulation & quarantine of new animals 2. Quarantine and remove positives 3 . Quarantine and remove positives, vaccinate susceptible animals 4. Quarantine and vaccination (or treatment)
32
Control and eradication option: animal depopulation and quarantine of new animals
– Highly contagious diseases, short incubation period (explosive) – Test and slaughter (entire herds, not individual animals) – Disease is disruptive to production and economy – Good diagnostic test is available (even though clinical recognition may be difficult) – No reservoir species exists – Quick response & outcome -examples: foot and mouth disease, bovine spongiform encephalopathy
33
Control and eradication option: quarantine and remove positives
– Agent is not highly contagious or communicable, there is a long incubation period, and infection is detectable during incubation period – Test and slaughter (individual animals) – Prevalence of the disease is low – Requires a diagnostic test – Not devastating enough to justify option #1 – Examples: Bovine TB, Equine infectious anemia
34
Control and eradication option: quarantine and remove positives, vaccinate susceptible animals
– Used when prevalence of disease is higher and segregation of the herds or populations is inadequate and the removal of positives will not stop transmission – Once prevalence is reduced and the herds closed, vaccination can be discontinued – Surveillance must be continued, positive/reactor herds quarantined, and positives eliminated – Example: Brucellosis
35
Control and eradication option: quarantine and vaccination/treatment
– Used when prevalence is high but economic & production costs are not catastrophic – Slows (but does not totally prevent) transmission to other animals/herds – Examples: Leptospirosis, Infectious bovine rhinotracheitis, Bordetella
36
Disease eradication: criteria for success (2 types)
Biological Social and political
37
Biological vs social and political criteria for disease eradication (general)
Biological = objective Social/political = subjective
38
Disease eradication: biological criteria for success
– An effective method is available to interrupt transmission – Practical diagnostic tools are available to detect infection – Only one vertebrate reservoir & no environmental amplification
39
Disease eradication: social and political criteria for success
– Societal/political will – Disease must be significant in terms of morbidity and/or mortality – Intervention & eradication must be technically feasible – Medical, scientific, and legislative bodies must agree on justification – Advocacy must exist for national/regional/global support – Focuses on one clear and unambiguous goal – Scope is clear and duration is limited
40
Bio safety level 1 labs
-work with least dangerous agents, require fewest precautions -Agents not known to cause disease in healthy adults – Some organisms may cause disease in immunocompromised individuals • Agents include Bacillus subtilis, Naegleria gruberi, infectious canine hepatitis virus, non-pathogenic E. coli species
41
bio safety level 4 labs
-have strictest methods because dealing with agents that are most dangerous to human health -Dangerous and exotic agents with high risk of life- threatening disease, aerosol-transmitted – Related agents with unknown risk of transmission • Agents (all viruses) include Marburg virus, Ebola virus, viruses that cause Congo-Crimean hemorrhagic fever, Lassa fever
42
Bio safety level 4 precautions
Bio safety lab 3 plus: – Highly specialized training in handling extremely dangerous infectious agents, containment equipment and functions – Strict access to lab; immunocompromised persons are never allowed to enter the lab – Standard practices include BSL-3 plus: Changing clothing before entering and exiting lab, showering at exit; Decontaminating all material exiting facility
43
Bio safety level 1 precautions
– Frequent handwashing – Limited access to the lab space when working; – No smoking, eating, drinking, storage of food in laboratory; – Minimize splashes and actions that may create aerosols; – Decontamination of work surfaces after every use or spill; – Decontamination of laboratory wastes; – Mechanical pipettes only (no mouth pipetting); – Sharps precautions for needles and other sharp objects; – Insect/rodent control program; – Personal protective equipment (lab coats, latex gloves, eye protection or face shields)
44
Bio safety level 2 labs
• Agents do not cause lethal infections, are not transmissible via airborne route • Agents are pathogens for which immunization or antibiotic treatment is available • Include measles virus, Salmonella species, pathogenic Toxoplasma, Clostridium botulinum, hepatitis B virus
45
Bio safety level 2 precautions
• Standard practices plus: – Greater access restrictions to lab; – Biohazard warning signs posted outside lab; – Surveillance & immunization of laboratory personnel; – biosafety manual with definitions of needed waste decontamination or medical surveillance policies; – supervisory staff who have experience working with infectious agents and specific training for laboratory personnel in handling these agents
46
Bio safety level 3 labs
• Agents with potential for respiratory transmission, may cause serious and potentially lethal infection • Either prevention or treatment options exist ( May be less effective than for BSL-2 pathogens) • Includes M. tuberculosis, St. Louis encephalitis virus,rabies
47
Bio safety level 3 precautions
• Biosafety level 2 plus: – Strictly controlled access to the lab; – Pathogen-specific training for lab personnel; – Decontaminating all waste; – Changing clothing prior to entering/exiting lab; – Policies for testing workers & storing samples
48
Primary barriers: biosafety level 1 vs 2 vs 3 vs 4
1- N/A 2- biosafety cabinets, containment 3- biosafety cabinets + respiratory PPE 4- biosafety cabinets + full body, air supplied, positive pressure personnel suit

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