BIOTECHNOLOGY Flashcards
(13 cards)
Gene ________ is the insertion of a functional gene into patients who suffer from a particular genetic disease because they have a mutation in that gene
Therapy
_____ technology enables us to move material from one species to another
Gene
The two type of gene therapy are what
Germ line gene therapy
Somatic gene therapy
_________ gene therapy is the insertion if recombinant genes into germ cells (ova or sperm) - the transgene would be ________
Germ line
Heritable
_______ gene therapy is the correction of genetic defects in ________ cells - the transgene is limited to the individual and is not hereitable take to the progeny
Somatic
Somatic
Is it legal asunder Australian law to perform germ line gene therapy on humans
No it’s illegal
Is it illegal under Australian law to perform somatic cell gene therapy on humans
No it’s legal to do so
Duchenne muscular dystrophy is a ________ x-linked disorder
Recessive
Duchenne muscular dystrophy is a disorder caused by a mutation in the ______ gene, located in humans in the short (p) arm if the X chromosome at position 21.2
dystrophin
Short
Dystrophin provides structural stability to the d__________ complex located on the cell membrane
Dystroglycan complex
The _________ complex connects the ________ of a muscle fibre to the surrounding extracellular matrix through the cell membrane
Dystroglycan
cytoskeleton
Matrix
____- associated viruses are being trailed for use in gene therapy for DMD
Adeno
AAV can insert the gene at a specific. Site and is _____
non-pathogenic