BIOTECHNOLOGY Flashcards

0
Q

Gene ________ is the insertion of a functional gene into patients who suffer from a particular genetic disease because they have a mutation in that gene

A

Therapy

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1
Q

_____ technology enables us to move material from one species to another

A

Gene

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2
Q

The two type of gene therapy are what

A

Germ line gene therapy

Somatic gene therapy

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3
Q

_________ gene therapy is the insertion if recombinant genes into germ cells (ova or sperm) - the transgene would be ________

A

Germ line

Heritable

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4
Q

_______ gene therapy is the correction of genetic defects in ________ cells - the transgene is limited to the individual and is not hereitable take to the progeny

A

Somatic

Somatic

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5
Q

Is it legal asunder Australian law to perform germ line gene therapy on humans

A

No it’s illegal

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6
Q

Is it illegal under Australian law to perform somatic cell gene therapy on humans

A

No it’s legal to do so

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7
Q

Duchenne muscular dystrophy is a ________ x-linked disorder

A

Recessive

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8
Q

Duchenne muscular dystrophy is a disorder caused by a mutation in the ______ gene, located in humans in the short (p) arm if the X chromosome at position 21.2

A

dystrophin

Short

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9
Q

Dystrophin provides structural stability to the d__________ complex located on the cell membrane

A

Dystroglycan complex

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10
Q

The _________ complex connects the ________ of a muscle fibre to the surrounding extracellular matrix through the cell membrane

A

Dystroglycan
cytoskeleton
Matrix

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11
Q

____- associated viruses are being trailed for use in gene therapy for DMD

A

Adeno

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12
Q

AAV can insert the gene at a specific. Site and is _____

A

non-pathogenic

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