Blastomycosis Flashcards Preview

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Flashcards in Blastomycosis Deck (13):
1

Blastomycosis is what type of infection?

Fungal

2

Blastomycosis is caused by what?

Fungus Blastomyces dermatitidis

3

Blastomycosis is primarily where? It can become what however?

Lungs; can become systemic

4

What are the symptoms of Blastomycosis?

Similar to influenza but ~ 50% exposed are asymptomatic

5

What increases the risk of Blastomycosis?

Diabetes and lower immune response

6

Where are the common reservoirs of Blastomyces dermatitidis found?

in some soils in wooded arease (Mississippi, and Ohioi Valley)

7

Blastomyces dermatiditis have what two forms?

yeast and mold forms

8

How do the two different forms of Blastomyces dermatiditis differ?

a) Yeast is a virulent form

b) Mold is environmental form

9

How is yeast able to escape macrophage killing?

it is is masked under 1, 3 alpha-glucan

10

How is Blastomyces dermatiditis diagnosed?

Microscopic detection of fungus in clinical samples and confirmation with culture

11

Treatement of Blastomyces dermatidis depends on what?

severity of infections and immune status of patient

12

What drug is used for treatment of systemic life threatening Blastomyces dermatidis?

Amphotericin B

13

What drug is used for treatment of mild/moderate Blastomyces dermatidis?

Azoles such as fluconazoles and itraconazoles