Flashcards in Candida albicans Deck (31):
Candida albicans is what type of infection?
Candida albican is what type of pathogen?
Candida albicans are common species of what?
Candida albicans can overgrow after what?
after antibiotic treatment
Candidasis thrush is an infection where?
Invasive (severe) candida albicans can cause what type of infections?
Systemic blood infections
Vaginitis is an infection where?
Vaginitis is also called what?
Vaginitis is characterized by what?
- white or yellow discharge
-burning or itching
-inflamation of vagina and vulva
The yeast form of C. albicans that cause vaginitis can grow as what?
fungi called pseudophyphae
How is vaginitis diagnosed?
Swab samples from vaginal infection?
what % woman experience vaginitis at least once in their lifetime ?
Vaginitis causes alterned normal flora of what?
Yeast colonizes what surfaces?
Hyphae colonize what surfaces?
Invades host tissues and mucosal epithelial cell layers; breaches endothelial cells.
Yeast can dissemination (spread) where in immunocompromised host?
into host tissues
Pseudohyphae hae what type of motility?
De facto motility
Pseudohyphae have what type of nutritional scavenging compared to yeast?
Enhanced nutrient scavenging compared to yeast
Hyphae can causes lysis to what?
macrophages and neutrophilis
Hyphae have thigmotropism which is what?
The bending or turning of the organism in response to a touch stimulus
hyphae have what antigen?
Have antigen variation
Can candida albicans grow as a biofilm?
Candida albicans biofilm infections are often asociated with what?
What is the treatment for Candida albican non invasive infections?
What is the treatment for systemic Candida albicans infection
Resistance mechanisms of Candida albican are similar to what? How?
bacteria; biofilm-specific gene expression, biofilm matrix, and efflux
What adhesion proteins does candida albican have?
-AIs1p, AIsp, Hwp1p, Int1p
What are the virulence factors of candida albican?
1) Adhesion proteins
2) Morphogenesis into invasive filaments
4) Phenotypic switching
What are the degradation enzymes of candida albican?
Phenotypical switching plays a role in what?
-altering yeast's adherence properties