Bleeding Disorders

Question 1

Diagnosis of a patient with recurrent epistaxis, episodes of heavy bleeding following medical procedures, bruises, normal bleeding time and prolonged PTT.

Answer 1

Hemophilia

Question 2

Von Willebrand disease presents with
- PT:
- PTT:
- Bleeding time:
- Platelet count:

Answer 2

• normal
• normal or increased
• increased
• normal

Question 3

What is the treatment for von Willebrand disease 1 or 2?

Answer 3

Desmopressin

Question 4

What is the most common inherited bleeding / coagulation disorder?

Answer 4

von Willebrand disease

Question 5

Patients with type 3 vW disease may be treated with:

Answer 5

recombinant von Willebrand factor (rvWF) and factor VIII concentrate.

Question 6

What is the treatment for hemophilia A?
- Mild:
- Severe:

Answer 6

• Mild: desmopressin Severe:
• Factor VIII concentrate

Question 7

In hemophilia A, mixing normal plasma with the patient’s plasma (mixing study)_____the PTT

Answer 7

does correct

Question 8

What is the likely diagnosis in an adolescent with a history of hemophilia A that presents with gradually worsening pain and limited motion of his knee?

Answer 8

Hemophilic arthropathy

Question 9

What is the mode of inheritance of hemophilia A and B?

Answer 9

X-linked recessive

Question 10

What is the treatment for a hemophilia B after head trauma?

Answer 10

Factor IX concentrate