BLI 35 - Drugs for HIV/AIDS

Question 1

Binds gp41

Answer 1

Enfuvirtide

Question 2

Prevents interaction with gp120

Answer 2

Maraviroc

Question 3

Fx: Protease Inhibitors inhibit _______

Answer 3

CYP3A4

Question 4

Hyperpigmentation

Answer 4

Emtricitabine (NRTI)

Question 5

2 drugs that decrease mother-to-newborn transmission

Answer 5

Zidovudine & Lamivudine

Question 6

Enfuvirtide

Answer 6

Attachment and fusion inhibitor

Question 7

2 drugs for treatment of HBV infection

Answer 7

Lamivudine

Tenofovir

Question 8

Liver injury

3A4 & 2B6 inducer

Answer 8

Nevirapine (NNRTI)

Question 9

Stavudine

Answer 9

NRTI

Question 10

Predisposed to hypersensitivty if given Abcavir

Answer 10

HLA-B*5701

Question 11

Ritonavir

Answer 11

Protease Inhibitor

Question 12

Etravirine

Answer 12

NNRTI

Question 13

Used in boosted therapy - combined with PIs to increase their plasma level and duration

Answer 13

Ritonavir

Question 14

Emtricitabine

Answer 14

NRTI

Question 15

Tenofovir

Answer 15

NRTI

Question 16

Teratogenic

Neuropsychiatric reactions

Answer 16

Efavirenz (NNRTI)

Question 17

Maraviroc

Answer 17

Attachment & fusion inhibitor

Question 18

Zidovudine

Answer 18

NRTI

Question 19

Pancreatitis & Peripheral neuropathy

Answer 19

Didanosine (NRTI)

Question 20

What are the two single pill regimens?

Answer 20

Efavirenz-Tenofovir-Emtricitabine

Rilpivirine-Tenofovir-Emtricitabine

Question 21

Subcutaneous injection

Answer 21

Enfuvirtide

Question 22

Abacavir

Answer 22

NRTI

Question 23

Antagonist of CCR5

Answer 23

Maraviroc

Question 24

Delavirdine

Answer 24

NNRTI

Question 25

Renal impairment

Answer 25

Tenofovir (NRTI)

Question 26

Raltegravir

Answer 26

Integrease inhibitor

Question 27

Hypersensitivity rxn due to HLA-B\*5701

Answer 27

Abcavir (NRTI)

Question 28

Didanosine

Answer 28

NRTI

Question 29

Efavirenz

Answer 29

NNRTI

Question 30

3 drugs used for drug-resistant strains of HIV

Answer 30

Enfuvirtide & Maraviroc (for those resistant to RTIs & PIs) Raltegravir (for those resistant to multiple anti-retroviral agents)

Question 31

Nevirapine

Answer 31

NNRTI

Question 32

Lamivudine

Answer 32

NRTI

Question 33

Pancreatitis only

Answer 33

Stavudine (NRTI)

Question 34

Atazanavir

Answer 34

Protease Inhibitor

Question 35

Bone marrow suppression

Answer 35

Zidovudine (NRTI)

Question 36

Anything with -**na**vir

Answer 36

Protease Inhibitor