Kasbari, Siddiqui, Rizzo Flashcards by Brian Duxbury

Q

Process that converts centroblast to centrocyte

A

Somatic hypermutation

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Q

Bcl-2

A

Follicular

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Q

>20% blasts

A

Accelerated phase of CML

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Q

Chronic inflammatory states

Hashimoto thyroiditis
H. pylor gastritis
Sjogren

A

Marginal Zone

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Q

Cyclin D1+

A

Mantle Cell

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Q

CD5/20

A

CLL/SLL

Mantle Cell

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Q

Basophiles increasd

A

CML

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Q

Hypogammaglobulinemia

ITP & AHA

A

CLL/SLL

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Q

gingival hyperplasia

A

AML

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Q

Virus associated with mixed cellularity CHL

A

EBV

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Q

Tx: ATRA

A

Acute promyelocytic

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Q

t(2;5)

A

ALCL

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Q

MPO

Auer rods

A

AML

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Q

t(8;14)

A

Burkitt

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Q

Smudge cell

Soccer ball appearance

A

CLL/SLL

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Q

Treat with imatinib

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A

CML

Q

TRAP

Dry tap

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A

Hairy Cell

Q

Centroblasts

>15 = stage III

< 15 = stage I or II

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A

Follicular

Q

2 medical emergencies

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A

Burkitt

T-ALL

Q

Transformation of CLL

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A

Diffuse Large B Cell

Prolymphocytic

ALL

Q

t(15;17)

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A

acute promyelocytic

Subtype of AML

Q

Colonic perforation from Ileocecal mass

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A

Burkitt

Q

Morphology of acute promyelocytic

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A

Bilobed nuclei

Auer rods

Q

CD34

TdT

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A

B-ALL

Decreased Leukocyte Alkaline Phosphatase (LAP)

CML

t(14;18)

CLL/SLL Follicular

Involves the jaw

Burkitt - Endemic (African)

CD10/20

Follicular Burkitt B-ALL

PML-RARA

Acute promyelocytic

CD15

CHL

Monocytopenia

Hairy Cell

c-myc

Burkitt

MALToma

Marginal Zone

CD30

CHL ALCL

ALK-1

ALCL

t(11;14)

Mantle Cell "mante-LL --\> 11"

Good prognosis AML's

t(15;17) t(8;21) t(16;16) or inv16

CD23

CLL/SLL