Block 3 - Immune System Flashcards Preview

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Flashcards in Block 3 - Immune System Deck (79):
1

aggregated nodules are made of blank

b lymphocytes

2

aggregated nodules of lymphocytes in pharyngeal region

tonsils

3

germinal centers are blank stained because of blank

lightly, immaturity

4

thin walled vessels that collect and transport intercellular fluid

lymphatics

5

lympatics have blank like veins

valves

6

lymphatics take lymph to and from blank

lymph nodes

7

largest lymphatic that is emptied into the venous system

thoracic duct

8

part of lymph node that is dense ct and continues as trabeculae

capsule

9

part of lymph node that has reticular cells, reticular fibers, and mixed phagocytic cells

stroma

10

reticular cells are aka

fibroblasts

11

reticular fibers are blank collagen

type 3

12

blank lymphatics bring lymph to the node

afferent

13

blank lymphatics bring lymph away from the node

efferent

14

layer of cortex that has nodules/b cells

outer

15

layer of cortex that has dense collection of t lymphocytes

inner

16

blank nodules have a circular solid mass of mature lymphocytes with some macrophages and dendritic cells

primary

17

blank nodules have a germinal center

secondary

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part of lymph node that has cords of b lymphocytes and numerous large sinuses lined by endothelial and phagocytic cells

medulla

19

b lymphocytes become blank cells which become blank

plasma cells, antibodies

20

medulla involves the formation of blank lymphatics

efferent

21

large lymphocytes that differentiate into mature cells

immunoblasts

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during maturation, lymphocytes get blank

smaller

23

blood vessels enter and exit lymph node at the blank

hilus

24

arteries become blank in cortex

capillaries

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capillaries become blank in deep cortex

post capillary venules

26

circulating lymphocytes have surface markers
called blank that recognize surface markers
on the high endothelium and emigrate venule
to enter lymph node

selectins

27

lymph node produces blank and traps blank

lymphocytes/antibodies, bacteria/foreign matter

28

white spots of spleen

white pulp

29

red spots of spleen

red pulp

30

darkly stained spots of spleen are lymphocytes and make up the blank

white pulp

31

spleen has a similar structure to lymph node due to these

capsule, stroma

32

white pulp makes up 20 % of spleen and has these

b/t lymphocytes

33

red pulp two divisions of spleen

venous sinuses, splenic cords

34

cant tell divisions of red pulp of spleen apart because they both are full of blank

blood

35

there is no blank in spleen

medulla

36

this runs through t cell masses and lymphoid follicles

central artery

37

red pulp sinuses has minimal blank and is encircled by few reticular fibers

basal lamina

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RBC become healthy in the splenic blank then squeeze into blank

cord, splenic sinus

39

narrow zone of modified red pulp adjacent to white pulp and receives blood from local small arterioles

marginal zone

40

marginal zone has blank sinuses and has blank presenting cells in the area

small, antigen

41

large bv in spleen are supported by blank

trabeculae

42

blood dumped into blank are exposed to local macrophages

splenic cords

43

blood cells are safe when passed into blank

splenic sinuses

44

blood flow pattern of spleen

Splenic artery --> trabecular artery --> central
artery (surrounded by lymphocytes) --> small
arteriole in red pulp --> penicilli arteries (which discharge/dump blood into splenic cord to enter sinuses via their slits) --> venule
draining sinus --> larger venule --> trabecular
vein --> splenic vein

45

spleen not only destroys aged rbc and produce lymphocytes, but it also sequesters blank to become blank

monocytes, macrophages

46

T lymphocytes come from blank

thymus

47

lymphocytes in thymus are cytologically isolated from blank

external stimuli

48

stroma of thymus is blank because it is derived from outpouchings of epithelium lining of the pharynx

epithelium

49

thymus release blank which teach immature lymphocytes how to become immune competent

cytokines

50

thymus has these cells forming the epithelial stroma of the thymus and are different from reticular cells and reticular fibers in lymph node and spleen

epithelial reticular cells

51

epithelial reticular cells of thymus are responsible for imparting blank of immature lymphocytes

immunocompetency

52

epithelial reticular cells form a blank barrier

blood-thymus

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cortex of thymus has a solid dark staining mass of blank

lymphocytes

54

undifferentiating lymphocytes come from bone marrow, enter cortex and move toward blank as they mature

medulla

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percent of T cells that are eliminated

95%

56

medullae of adjoining lobules of thymus look blank

continuous with each other

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medulla of thymus stains blank due to blank

pale, fewer lymphocytes

58

unique focal, concentric clumps of epithelial reticular cells that become cornified... part of thymus

thymic/hassal's corpuscles

59

hassall's corpuscles increase with blank

age

60

as we get older, the concentration of blank diminishes and cortico medullary distinction is blank

lymphocytes, lost

61

two types of immunity performed by lymphocytes

humoral, cell mediated

62

blank immunity is manifested by production of antibodies by plasma cells

humoral

63

humoral immunity does not require cells presence for blank to react with blank

antibody, antigen

64

immunity where the cells presence is required as it performs a function like killing a cell

cell mediated immunity

65

two types of lymphocytes

T, B

66

origin of b cells in birds

bursa of fabricius

67

lymph nodes, spleen, etc are considered blank lymphoid organs since they don't develop there

secondary

68

lymphoid organ attached to cloaca in birds

bursa of fabricius

69

human equivalent to bursa of fabricius

bone marrow

70

three types of t cells

helper, killer (cytotoxic), suppressor

71

percent of lymphocytes in blood that are t

80

72

percent of lymphocytes in blood that are b

15%

73

cant tell the difference between blank and blank lymphocytes

t,b

74

b cells only function in blank infection

bacterial

75

t cells function blank unlike b cells

intracellularly

76

cd 4 t cells are blank t cells

helper

77

cd8 t cells are blank t cells

cytotoxic

78

helper t cells help mark antigen for blank cells

t, and b

79

killer t cells also release blank which enter target cell and mess up metabolism so it undergoes apoptosis

granzymes