Flashcards in Block C Deck (269)
renin is secreted by
how does urinary system regulate blood calcium
hydroxylation of vitamin D
inner layer of kidney capsule consists of mainly
between medullary rays are
kidney lobule consists of
single medullary ray plus adjacent 1/2 of the cortical labyrinth on each side
a kidney lobule consists of
all nephrons associated with a single medullary duct
papillary duct of bellini opens into the
minor calyx at the renal papilla
where are thin parts of juxtamedullary nephron?
on ascending and descending sections
mid-cortical nephron extends to
inner stripe of outer medulla
where are thin parts of mid cortical nephron?
only the descending section
what is contained in outer stripe of outer medulla?
only thick tubular segments and outer medullary collecting ducts
what is contained in the inner stripe of outer medulla?
thick and thin tubular segments and outer medullary collecting ducts
uriniferous tubule =
nephron + collecting ducts
numerous uriniferous tubules are associated with a papillary duct, which makes up a
the initial formed urine in bowman's space is called
_______ lie outside the glomerulus between arterioles and help maintain strucutre
extraglomerular mesangial cells/Lacis cells
do podocytes regenerate?
the basement membrane of the proximal convoluted tubule is continuous with the
basal lamina of the glomerular capillaries
glomerular basement membrane-
fused membrane with three layers representing the fusion of the basal lamina of the endothelial cells and the podocytes.
3 layers of glomerular basement membrane-
lamina rara externa, lamina densa, lamina rara interna
pedicels limit molecular passage by
slit size and anionic charge
filtration slit diaphragm is anchored into the pedicels via
components of the glomerular basement membrane- (5)
type 4 collagen, laminin, fibronectin, heparin sulfate, proteoglycans
pedicels are anchored to the basal laminae by
_____ forms the core of the pedicels
what 4 molecules join nephrin and actin to make the GFB
neph1, neph2, fat1 and fat2
mesangial cells secrete _________ to cause vasoconstriction
prostaglandins and endothelins
______ cells control GBM material turnover
mesangial cells respond to _______