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Flashcards in Block C Deck (269)
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1

renin is secreted by

juxtaglomerular cells

2

how does urinary system regulate blood calcium

hydroxylation of vitamin D

3

inner layer of kidney capsule consists of mainly

myofibroblasts

4

between medullary rays are

cortical labyrinths

5

kidney lobule consists of

single medullary ray plus adjacent 1/2 of the cortical labyrinth on each side

6

a kidney lobule consists of

all nephrons associated with a single medullary duct

7

papillary duct of bellini opens into the

minor calyx at the renal papilla

8

where are thin parts of juxtamedullary nephron?

on ascending and descending sections

9

mid-cortical nephron extends to

inner stripe of outer medulla

10

where are thin parts of mid cortical nephron?

only the descending section

11

what is contained in outer stripe of outer medulla?

only thick tubular segments and outer medullary collecting ducts

12

what is contained in the inner stripe of outer medulla?

thick and thin tubular segments and outer medullary collecting ducts

13

uriniferous tubule =

nephron + collecting ducts

14

numerous uriniferous tubules are associated with a papillary duct, which makes up a

kidney lobule

15

the initial formed urine in bowman's space is called

ultrafiltrate

16

_______ lie outside the glomerulus between arterioles and help maintain strucutre

extraglomerular mesangial cells/Lacis cells

17

do podocytes regenerate?

no

18

the basement membrane of the proximal convoluted tubule is continuous with the

basal lamina of the glomerular capillaries

19

glomerular basement membrane-

fused membrane with three layers representing the fusion of the basal lamina of the endothelial cells and the podocytes.

20

3 layers of glomerular basement membrane-

lamina rara externa, lamina densa, lamina rara interna

21

pedicels limit molecular passage by

slit size and anionic charge

22

filtration slit diaphragm is anchored into the pedicels via

nephrin

23

components of the glomerular basement membrane- (5)

type 4 collagen, laminin, fibronectin, heparin sulfate, proteoglycans

24

pedicels are anchored to the basal laminae by

integrin

25

_____ forms the core of the pedicels

actin

26

what 4 molecules join nephrin and actin to make the GFB

neph1, neph2, fat1 and fat2

27

mesangial cells secrete _________ to cause vasoconstriction

prostaglandins and endothelins

28

______ cells control GBM material turnover

mesangial cells

29

mesangial cells respond to _______

angiotensin II

30

lateral cell boundaries of proximal convoluted tubules are indistinguishable because of

lateral infoldings/plicae