Blood Flashcards

Exam 2 (85 cards)

1
Q

what are the 2 circulatory systems

A

cardiovascular
lymphatic

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2
Q

is the cardiovascular system a closed or open system

A

closed, the blood doesnt leave the loop

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3
Q

is the lymphatic system a closed or open system

A

open system, it picks up excess ECF and returns to CV system

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4
Q

what are the 3 main componenets of the cardiovascular system

A

heart
blood vessels
blood

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5
Q

what are the 3 overarching functions of blood

A

transport
regulation
and protection

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6
Q

what does blood all transport

A

gases
nutrients
waste products
hormones
proteins

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7
Q

what are the gases that blood transports

A

co2 and o2

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8
Q

ex of nutrient that blood transports

A

glucose

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9
Q

examples of waste products that the blood transports

A

lactic acid, urea protein breakdown products

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10
Q

where are most proteins transported by the blood actually synthesized

A

the liver

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11
Q

what is albumin

A

a major contributor to blood osmolarity and is a nonspecific binding protein

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12
Q

what are other proteins transported by the liver

A

globins like antibodies or binding proteins
clotting factors
and enzymes

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13
Q

what are 3 ways that blood acts in regulation

A

distribution of heat
to be a buffer
electrolyte balance

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14
Q

how does blood regulate/distribute heat

A

heat is picked up from muscle maintains normal body temp
body can do vasoconstriction of superficial dermel blood vessels to retain heat OR
can do vasodilation of superficial dermel blood vessels to red of excess heat

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15
Q

does vasoconstriction retain or rid heat

A

retain

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16
Q

does vasodilation retain or rid heat

A

rid

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17
Q

what is the normal blood pH

A

7.35 to 7.45

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18
Q

what does albumin bind to

A

excess H+ ions

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19
Q

what can hemoglobin bind

A

also excess H+ ions

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20
Q

what does the Na+/K+ pump affect

A

nerve conduction and skeletal muscle contraction

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21
Q

what does Ca++ affect

A

cardiac muscle activity contraction

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22
Q

what are the 2 ways that blood aids in protection

A

immunity and clotting

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23
Q

what part of the blood aids in immunity

A

leukocytes (WBC)

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24
Q

what part of the blood aids in clotting

A

thrombocytes (platelets)

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25
what 2 large components make up whole blood
formed elements and plasma
26
what 3 componenets make up formed elements
erythrocytes leukocytes thrombocytes
27
how much percent do formed elements take up in whole blood. plasma ?
45 % and plasma is 55%
28
info on erythrocytes
red blood cells, 99% of cells, med size, bicon caved disc, no nucleus
29
info on leukocytes
carry O2, are white blood cells, large, round, have nucleus, immunity
30
info on thrombocytes
they are platelets, like cell fragments, no nucleus, quite small
31
break up plasma components by components
water - 92 % proteins, ions, nutients, waste products, gases, etc. - 8%
32
what i serum
plasma - clotting
33
hematocrit def
% whole blood made up of cells by vol 45 % % of RBC in whole blood
34
HCT =
PCV/TV *100 RBC/TOTAL
35
what does anemia do
decrease o2 carrying capacity (<30% HCT)
36
polycythemia is what
blood is to thick, more viscous (>60% HCT)
37
why can you give plasma more than blood
plasma is mostly h2o and can be replenished quicker than blood
38
Benefits of thin blood
flows easier, heart works less hard, low blood pressure
39
negatives of thin blood
bleeding disorder, hypotension, anemia, low immunity
40
benefits of thick blood
more o2 available, increased immunity
41
negatives of thick blood
hypertension, increases viscosity, heart works harder, increased clotting
42
does thin or thick blood have high HCT
thick blood
43
what is hypoxia
low o2 at tissue because hemoglobin is abnormal. this damages capillaries, decreases blood flow, and slows breathing
44
what are legitimate reasons for taking erethroprotein
kidney disease, anemia, altitide sickness
45
what are illegitimate reasons for taking erethroprotein
athletes to enhance performance
46
blood color, why? O2 vs deoxygneated?
red because of hemoglobin deoxygenated is a dusty red/brown but is drawn as blue
47
quantitiy of blood in body
4-6 L ~ 8 % of bw
48
specific gravity of blood
1.06
49
ph range of blood
7.35 to 7.45
50
why do erythrocytes have an increased surface area
for absorption of o2
51
how much space does hemoglobin take up on an erythrocyte
1/3 volume of cell
52
do erythrocytes have a nucleus or mitochondria ?
no, neither
53
lifespan of an erythrocyte
120 day
54
shape of erythrocytes (RBC)
biconcave disk
55
what does hemoglobin do
carry o2
56
what does globin mean in hemoglobin
protein 4 peptide chains
57
what does heme mean in hemoglobin
ring strucutre iron
58
what does iron bind
o2 and co2
59
what binds easier,,, o2 or co2
co2
60
what is erythropoiesis
formation of red blood cells
61
what is a hemocytoblast
blood stem cells that are found in red bone marrow
62
phagocytosing of erythrocyte
to a worn out RBC, they fuse vesicle with lysosome, which seperates protein from heme
63
why is recycled in erythrocyte degradation
amino acids and iron
64
Bili what now>
bilverdin- green bilirubin- yellow
65
what is a type of anemia that is genetic
sickle cell anemia
66
what causes hemolytic anemia
RBC lyse
67
what is pernicious anemia
cant produce intrinsic factors that allow for absorption of iron
68
ABO gene is located on what chromosome
9
69
Rh factor gene is located on what chromosome
1
70
what does the glycosyltransferase enzyme do
modifies CHOs
71
what are the types of blood in the ABO system
Type A, B, AB, and O
72
what are the types of blood in the Rh factor
Rh + and Rh -
73
what do the Rh factor mean in antigen terms
D antigen
74
what does Rh factor code for
gene codes for ammonia transporter
75
Type A + blood antigens and antibodies
A and D antigens anti B antibodies
76
Type B+ blood antigens and antibodies
B and D antigens anti A antibodies
77
Type AB+ blood antigens and antibodies
A, B, and D antigens no antibodies
78
type O+ blood antigens and antibodies
D antigens Anti A and B antibodies
79
Type A- blood antigens and antibodies
A antigens anti b antibodies
80
type B- blood antigens and antibodies
b antigens anti A antibodies
81
type AB- blood antigens and antibodies
A and B antigens no antibodies
82
Type O- blood antigens and antibodies
no antigens anti A and B antibodies
83
exposure to A and B antigens is due to what
gut fluera
84
what is the only time you make anti d
if you are Rh - and exposed to someone elses blood
85
what is agglutination
when blood clumps due to antibody-antigen interactions