Blood part 2 (cells) Flashcards

(53 cards)

1
Q

what is erythroblastosis fetalis

A

hemolytic disease of newborn
see immature RBC in sample of blood

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2
Q

when does erythroblastosis fetalis occus

A

when mother is (-) and fetus is (+)

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3
Q

if anti d antibodies cross placenta and enter fetus’s blood then what

A

rxn of aggulination followed hemolysis

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4
Q

how to prevent erythroblastosis fetalis

A

rhogam=anti d antibodies
passive immunization to prevent your own immune system from responding.
administered twice… at 20 wks if mom is Rh- and after birth if infant is Rh+

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5
Q

5 types of leukocytes from most to least commeon

A

neurophils, lymphocyte, monocyte, eosinophils, basophils

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6
Q

what are the 3 granulocytes

A

neutrophils, eosinophils, basophils

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7
Q

what are the 2 agranulocytes

A

lymphocyte, monocyte

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8
Q

what does granulocytes mean

A

the cell has granules

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9
Q

hemopoiesis def

A

process of how blood cells are formed in the body

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10
Q

what are most blood cells developed from

A

myeloid stem cellsw

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11
Q

what is the stem cell for all blood cell types

A

hemocytoblasts

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12
Q

what do lymphoid stem cells make, where does that mature?

A

lymphocyte and mature steps are not in bone marrow

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13
Q

Neutrophils size

A

med to large

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14
Q

neutrophils nuclus info

A

segmented nucleus, 3 to 5 segments

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15
Q

neutrophils function

A

phagocytosis

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16
Q

eosinophils size

A

med to small

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17
Q

eosinophils nuclus info

A

biolobed nucleus, 2 lobes

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18
Q

eosinophils function

A

phagocytosis,
anti inflammatory chemicals

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19
Q

basophils size

A

med to small

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20
Q

basophils nuclus info

A

bilobed nuclus, but is obscured by the dark staining granules

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21
Q

basophils function

A

phagocytosis
secrete histamine and heparin

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22
Q

histamine def

A

inflammatory chemical.
a vasodilator, increase blood flow to infected area and increase permeability of blood vessel wall to white blood cell

23
Q

heparin def

A

prevent blood clotting

24
Q

lymphocytes size

A

small to large

25
lymphocytes nucleus info
large, round nucleus
26
lymphocytes function
secrete t and b cells
27
t cells info
found in thymus, is a cell mediated immunity, it perforates cell membranes and kills cell
28
b cells info
found in bone marrow, and they produce antibodies
29
what WBC can live for years and remember encountering illness
lymphocytes
30
monocytes size
large
31
monocytes nuclues info
kidney, shaped nucleus
32
monocytes function
phagocytosis
33
what do monocytes become if they leave blood
macrophages
34
what can macrophages differentiate into
microglia or osteoclast
35
what are thrombocytes
platelets
36
thrombocytes size
very small
37
do thrombocytes have a nucleus
no
38
thrombocytes function
clotting
39
how do thrombocytes clot
they contain chemicals that are part of the clothing cascade they stick together if activated to form a platelet plug
40
3 steps fo blood clotting
vascular spasm formation of platelet plug coagulation
41
what are the 2 ways a blood clotting cascade can start
intrinsic mechanism and extrinsic mechanism
42
what factor connects extrinsic and intrinsic mechanism
factor X
43
where are many clotting factors produced
by the liver, inactive forms in blood
44
what are the 3 types of blood clotting disorders that we talked about
hemophilia, hemorrhage, thrombus/embolism
45
what is hemophilia
a genetic disease, lack one or more clotting factors therefore, blood does not clot properly
46
hemorrhage info
sudden loss of blood transfusion= formed elements and saline
47
thrombus/embolism info
thrombus is a stationary blood clot embolism is a traveling blood clot
48
what are the 4 anticoagulants
heparin, coumarin, aspirin, tissue plaminogen activator
49
heparin info
a natural anticoagulant made by humans, inhibit factor IX
50
coumarin info
rat poison, causes internal bleeding inhibits vit K, need to synthesize 4 clotting factors
51
aspirin info
inhibits thromboxane, needed for platelet and prevent platelets from releasing granules
52
tissue plasminogen activator info
breaks up clots
53
blood has several functions which are associated with the what
componenets that make up blood