Blood Cell Components

Question 1

Erythrocytes normal count

Answer 1

4.2-6.2 million erythrocytes/mm3

Question 2

primary responsibility for erythrocyctes

Answer 2

Tissue oxygenation

Question 3

Difference in RBC among men and women %

Answer 3

men 48%

women 42%

Question 4

5 kinds of Leukocytes

Answer 4

neutrophils
lymphocyctes
monocytes
eosinophils
basophils

Question 5

what are the 2 categories of leukocytes

Answer 5

granulocytes

aranulocyctes

Question 6

3 kinds of granulocytes

Answer 6

neutrophils (50-67%)
eosinophils 0-3%
basophils 0-2%

Question 7

2 kinds of aranulocytes

Answer 7

lymphocytes 24-40%

monocytes/macrophages 4-9%

Question 8

4 characteristics of neutrophils

Answer 8

First to arrive at site of inflammation​
Bands andsegs​
Increase with acute bacterial infections and trauma​
Shift to the left (increase of bands)​

Question 9

2 characteristics of lymphocyctes

Answer 9

Primary cells of immune response​

Increase with chronic bacterial infection and acute viralinfection​

Question 10

2 characteristics of monocytes

Answer 10

Phagocytosis​

Increase with bacterial infections & cancers

Question 11

2 characteristics of Eosinophils

Answer 11

Increase with allergic reactions or parasiticinfections​

Worms, wheezes, and weird diseases

Question 12

Basophils​ characteristics

Answer 12

Increase with allergic reactions (hypersensitivities, inflammatory reactions)

Question 13

What is hemoglobin Hgb

Answer 13

Measures amount of hemoglobin in your blood (oxygen carrying capacity

Question 14

normals for Hgb

Answer 14

Men 13.5-17.5g/dL

Women 12-15.5 g/dL

Question 15

cause for low Hgb

Answer 15

bleeding, folate/B12 deficiencies, cancers, kidney & liver disease

Question 16

cause for high Hgb

Answer 16

polycythemia, COPD, high altitude, heavy smoking

Question 17

What is Hematocrit Hct

Answer 17

Percentage of blood that is made up of packed red blood cells (RBCs
Interpreted in percentages
A hematocrit of 40% indicates that there are 40mL of packed RBCs in 100ml of blood

Question 18

Hct normal levels

Answer 18

Male: 41-50%
Female: 36-44%

Question 19

low Hct

Answer 19

anemia, bleeding, bleeding disorders, FLUID IMBALANCES

Question 20

high Hct

Answer 20

polycythemia, COPD, dehydration, shock, congenital heard disease

Question 21

red cell count

Answer 21

• # of erythrocytes in the blood

Question 22

mean corpuscle volumve MCV

Answer 22

size of erythrocytes

Question 23

Mean corpuscle hemoglobin (MCH

Answer 23

amount of hemoglobin in erythrocyte by weight

Question 24

WBC Total Count

Answer 24

5,000-10,000/mm3
Increased= leukocytosis 
Decreased= leukopenia
Decreased neutrophils= neutropenia 
Total counts degree of response to a pathological process

Question 25

Complete blood count = CBC

Answer 25

``` WBC Platelet RBC Hct Hb ```

Question 26

WBC with Diff

Answer 26

2 Components Total number of WBC’s in mm3 Is an absolute number (XXX thousand WBC/mm3) Determination of the proportion of each of the 5 WBC’s in a sample of 100 WBC’s Is a percentage in the sample of 100

Question 27

CBC WITH DIFF INTERPRETATION

Answer 27

An increased % in one type means a decrease in % of another type

Question 28

Neutropenia =

Answer 28

low neutrophil caount | < 1000/mm3

Question 29

when does neutopenia mostly occur

Answer 29

in cancer patients as result of disease or treatment

Question 30

What does neutropenia make someone susceptible to

Answer 30

bacterial infection

Question 31

4 precautions for neutropenic

Answer 31

Good hygiene Avoid contact with people who are sick Avoid raw fruits, vegetables, grains Keep door closed

Question 32

Leukopenia Pharmacologic Treatment | Hematopoietic agents (HA)

Answer 32

Class- Granulocyte Colony stimulating factors (G-CSF) Medication- Filgrastim (Neupogen) - leukopoietic growth factor produced by recombinant DNA technology

Question 33

MOA of Filgrastim

Answer 33

promotes proliferation, differentiation, activation of cells that make granulocytes

Question 34

Indications of Filgrastim

Answer 34

``` malignancies, chemo-induced leukopenia, bone marrow transplant, harvesting of hematopoietic stem cells, chronic neutropenia ```

Question 35

Routes of filgrastim

Answer 35

IV,SQ

Question 36

Adverse effects of filgrastim

Answer 36

bone pain, leukocytosis

Question 37

Pegfilgrastim (Neulasta)

Answer 37

long acting derivative of filgrastim

Question 38

MOA of Pegfilgrastim

Answer 38

increased production of neutrophils

Question 39

route of Pegfilgrastim

Answer 39

SQ

Question 40

A/E of Pegfilgrastim

Answer 40

bone pain

Question 41

half life for Pegfilgrastim

Answer 41

17 hours

Question 42

T/F Pegfilgrastim can cause peglyated and what does that mean?

Answer 42

True, delayed excretion by the kidneys