blood coagulation and clotting cascade Flashcards Preview

BIO407 > blood coagulation and clotting cascade > Flashcards

Flashcards in blood coagulation and clotting cascade Deck (10)
Loading flashcards...
1
Q

clot

A

a red gelatonous mass

2
Q

where do clots form and why do they form there?

A

they for in the vein/capillaries/small arterioles because pressure of the blood flow blows out clot in large arteries

3
Q

prothrombin

A

inactive form of thrombin- activated when needed

4
Q

extrinsic pathway

A

tissue damage caused release of tissue factor which activates factor then 10 then prothrombin to thrombin

5
Q

intrinsic pathway

A

damage to the exposed endothelial surface this activates a cascade leading to factor X (exposing underlying endothelial surface) to factor 10 which converts prothrombin to thrombin

6
Q

similarities between intrinsic and extrinsic pathways

A

turns prothrombin into thrombin

7
Q

chelating agents

A

removes calcium from the blood. this removes one of the factors which means no clot add back in the calcium and you can determine clot times and factor deficiencies

8
Q

Collagen exposed

A

VWF binds to tisse and begins cascade

9
Q

role of platelets

A

get trapped to VWF, then factor 7 attaches, platelets will accumulate

10
Q

platelet plug

A

made fast and controls the whole coagulation response