blood coagulation and clotting cascade

Question 1

clot

Answer 1

a red gelatonous mass

Question 2

where do clots form and why do they form there?

Answer 2

they for in the vein/capillaries/small arterioles because pressure of the blood flow blows out clot in large arteries

Question 3

prothrombin

Answer 3

inactive form of thrombin- activated when needed

Question 4

extrinsic pathway

Answer 4

tissue damage caused release of tissue factor which activates factor then 10 then prothrombin to thrombin

Question 5

intrinsic pathway

Answer 5

damage to the exposed endothelial surface this activates a cascade leading to factor X (exposing underlying endothelial surface) to factor 10 which converts prothrombin to thrombin

Question 6

similarities between intrinsic and extrinsic pathways

Answer 6

turns prothrombin into thrombin

Question 7

chelating agents

Answer 7

removes calcium from the blood. this removes one of the factors which means no clot add back in the calcium and you can determine clot times and factor deficiencies

Question 8

Collagen exposed

Answer 8

VWF binds to tisse and begins cascade

Question 9

role of platelets

Answer 9

get trapped to VWF, then factor 7 attaches, platelets will accumulate

Question 10

platelet plug

Answer 10

made fast and controls the whole coagulation response