Hemopoesis Flashcards

(11 cards)

1
Q

Erythropoesis

A

Reticulocyte nucleus shrinks and disappears

and retain enough metabolic activity to maintain membrane, hemoglobin, anabolic metabolism

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2
Q

what is needed to produce RBCs

A

membrane, hemoglobin, anabolic metabolism

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3
Q

How long does erythropoiesis take?

A

about 8 days

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4
Q

what is required for RBC to form

A

iron, B12, folic acid

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5
Q

normal number of RBC

A

5x10^2/ liter

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6
Q

Leukopoesis

A

lymphocyte progenitors migrate to the tissues to mature

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7
Q

circulating granulocytes are

A

mature and ready to act

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8
Q

circulating monocytes are

A

immature and develop into macrophages

numbers vary based on the type of growth factor that is released

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9
Q

Thrombopoiesis

A

Derived from megokaryocyte in the bone marrow and produced by fragmentation not mitosis

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10
Q

Formation of a megakaryocyte

A

cytoplasm develops a vesicle
membrane becomes discontinuous
Sheds cytoplasmic fragments into blood through sinusoids of bone marrow

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11
Q

noral platelet conts

A
250x10^9 
average life span- 3 days 
spleen holds 1/3 of total reserve
controlled by: hormone thrombopoietin 
growth factor
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