Blood Components Flashcards
(38 cards)
Name the 7 main functions of blood
1- Gas transport and exchange - co2+o2
2- maintaining body temp: removes heat via skin
3- distributing solutes
4- blood clotting + sealing blood vessels (platelets)
5- immune function (leukocytes and immune proteins)
6- maintaining BP via blood volume regulated at kidneys
7- plasma as a buffer (acid base homeostasis)
Name the 3 cell types in blood
Erythrocytes- RBCs
Leukocytes - WBCs
Thrombocytes- platelets
How much % of blood is plasma
55%
What is the hematocrit
Cell volume of RBCs in the blood
How much leukocytes and thrombocytes in blood (buffy coat)
1%
Which substance seperates blood contents in tube
Anticoagulant
Why are RBCs at the bottom of tube when blood is seperated
Because they contain Fe
What are the 2 main functions of plasma
Thermoregulation
Transport of molecules and gases
Why is high h20 content in plasma important for thermoregulation (90%)
It has high thermal capacity which means it can carry heat to the skin surface when too hot
Name the 3 plasma proteins present and which is most abundant
1- albumins : MOST
2- globulins a b y d
3- clotting (fibrinogen)
What is albumin most important role and where is it made
Made in liver
It’s important in osmoregulation
It carries steroid hormones and Lipids too which are hydrophobic (can’t mix in plasma)
What are globulin role in the body
Transport ions(like fe), Lipids and hormones
Also make up immune proteins like antibodies
Where are clotting proteins (fibrinogen) made and their purpose
Made in liver
Needed for blood clotting
Why can plasma cancer cells be identified compared to normal via gel electrophoresis
Because there will be a different amount of globulins, fibrinogen or albumin
Other than plasma proteins and water, what else is in plasma
Dissolved molecules like:
Nutrients (aa, Lipids, glucose)
Waste (biliruben), urea etc
Gases o2 and co2
Hormones
Why is erythrocytes biconcave shape important
Large sa:v ratio
Short diffusion pathway for o2 and co2 to lungs
How long do RBCs last until death
120 days
Why don’t rbc use oxygen themselves
No organelles like mt to use it for respiration
What is the mean cell volume (hemotacrit) measured in
Femtolitres
What is small rbc anemia called
Microcytic fe anemia
What is large rbc anemia called
Macrocytic anemia (less of them)
Which bone marrow stem cells differentiate into different blood cells
Multipotent haematopoietic stem cells
After the haematopoietic stem cells what is the next 2 divisions
Common myeloid progenitor
Lymphoid progenitor
What is made by the common myeloid progenitor
Megakaryocytes
Rbc
Mast cell
Myeloblast
