Blood Diseas

Question 1

Most common type of anemia world wide

Answer 1

Iron deficiency Anemia

Question 2

special stain that can stain iron

‘

Answer 2

.. Perl’s Prussian Blue stain

Question 3

How iron is stored in the body

Answer 3

15-20% of total iron in the body is stored as 1-ferritin which is small soluble
molecule that circulate into the blood
2-larger one called hemosiderin
(insoluble) and it’s present only in tissues like, in bone marrow, liver and spleen
And the other is present in hemoglobin insider the RBCs

Question 4

Normal loss of body iron

Answer 4

only by shedding skin and mucosal
epithelium especially from the GI (no excretion from human body by
urine or stool)

Question 5

Dietary iron is either present as

Answer 5

Heme (red meat animal source) or

non-heme(inorganic iron, vegetarian source)

Question 6

Hepcidin

Answer 6

hormone secreted from liver, and it’s important for the
homeostasis of iron; normally it inhibits iron absorption in the GI system
(Degrade ferroportin which are receptors or transport channels for iron
which are located in the small bowel cells “enterocytes

Question 7

-Causes of iron deficiency

Answer 7

Chronic blood loss

Dietary
. Decreased absorption

Hypochlorhydria

Increased demands

Myeloproliferative neoplasms