Blood film practical Flashcards

1
Q

What is normocytic?

A

Normal sized RBC but low number

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2
Q

What is microcytic?

A

Small RBC and low MCV

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3
Q

What does infraction in sickle cell disease lead to?

A

Bone necrosis and stroke

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4
Q

What does Haemolysis lead to?

A

Anaemia, jaundice and gallstones

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5
Q

What is the inheritance pattern of sickle cell disease?

A

Autosomal recessive

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6
Q

What are reticulocytes?

A

Immature RBC (new), may be misshaped

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7
Q

What are acanthocytes?

A

is applied to a cell with a few irregular projections- most commonly seen in liver disease

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8
Q

What are echinocytes?

A

generally have many short, sharp projections that are relatively evenly spaced on the cell.

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9
Q

What are schistocytes?

A

fragmented RBC that can be found as triangular, helmet shaped, or comma shaped with pointed edges.

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10
Q

What does Myeloma lead to (what causes it)?

A

Marrow infiltration

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11
Q

What does lack of raw material lead to?

A

Iron deficiency

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12
Q

What does renal failure lead to?

A

Erythropoietin deficiency

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13
Q

What does fragmentation in circulation lead to?

A

Disseminated intravascular coagulation

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14
Q

What is MCV?

A

Mean corpuscular volume is a measurement of the average size of a single red blood cell

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15
Q

What is MCHC?

A

Mean corpuscular haemoglobin concentration is the calculation of the amount of hemoglobin per unit volume in a single red blood cell.

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16
Q

Where are target cells mostly seen in? What are they also called?

A

Iron deficiency. Codocytes

17
Q

What is the appearance of a target cell?

A

have the appearance of a shooting target with a bullseye

18
Q

What is polychromasia?

A

disorder where there is an abnormally high number of immature red blood cells found in the bloodstream as a result of being prematurely released from the bone marrow during blood formation. (poly- refers to many, and -chromasia means color.)

19
Q

Increase in Hb, MCV and RDW means?

A

Received oral iron

20
Q

What is the best single test of iron stores in a patient?

A

Serum ferritin