Blood transfusion Flashcards Preview

Haematology > Blood transfusion > Flashcards

Flashcards in Blood transfusion Deck (24):
1

what antigens does o blood have

none

2

what antibodies does o blood have

anti A and anti B

3

why can you give o blood to someone who doesn't know their blood group

because it has no antigens so if give tosomeone with a blood group their antibody wont attack the o blood

4

what antigen and antibodies does A blood have

A antigen, anti B antibody

5

what antigen and antibodies does B blood have

B antigen, anti A antibody

6

what antigen and antibodies does AB blood have

no antibodies. A and B antigen

7

what blood should you give someone who doesn't know their blood type

group o and rhesus negative

8

what is required in haemorrhage

fluids including plasma expanders to maintain volume and red cell concentrates. packed red cells so haematocrit >70%

9

when is red cell transfusion indicated

replace massive loss, correct anaemia

10

when are platelets needed

only if bleeding, or if count is

11

FFP indications

correct clotting defect- liver disease, DIC, TTP

12

cryoprecipitate indications

source of fibrinogen

13

human albumin solution indications

for protein replacement. 20% albumin in hypoproteinaemia patient- liver disease, nephrosis

14

what is a massive blood transfusion

replacement of individuals entire blood volume within 24h. complications- decr platelets, decr Ca, decr clotting factors, incr K, hypothermia

15

when would a white cell transfusion be indicated

neutropenic sepsis

16

early complications (within 24h)

acute haemolytic reactions, anaphylaxis, bacterial contamination, febrile reaction, allergic reactions, fluid overload, acute lung injury

17

delayed complications (after 24h)

infections, iron overload, GVH disease, post transfusion purpura

18

what is post transfusion purpura

potentially lethal fall in platelets requiring IV Ig and platelet transfusions

19

what is a haemolytic transfusion reaction

incompatible blood- chest abdo pain vomiting, dyspnoea, headache. fever tachy hypotension DIC. stop transfusion

20

symptoms anaphylaxis

bronchospasm, cyanosis, hypotension, soft tissue swelling. stop transfusion

21

what can circulatory overload lead to

pulmonary oedema. give furosemide if dyspnoea, hypoxia, tachy, incr JVP, basal creps

22

what is transfusion related acute lung injury

dyspnoea, cough, CXR white out. stop transfusion

23

what is non haemolytic transfusion reaction

febrile reaction- shivering and fever - slow or stop the transfusion. paracetemol

24

what are the signs of allegic reactions to the transfusion

urticarial and itch. slow or stop transfusion. chlorphenamine