BM2_MICRO_Q3 Flashcards by My Wallet Is Dead

Effect of B19 parvovirus on fetus: *
Hydrops fetalis
Pure red cell aplasia
Fifth Disease
Erythema Infectiosum

Hydrops fetalis

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What type of specimen would be most appropriate for detection of adenovirus types 40 and 41 infection? *
Blood
Urine
Stool
Swab

Stool

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Types of Adenoviruses that are found most often in bone marrow and renal transplant recipients. *
Types 15 and 16
Types 11 and 12
Types 40 and 41
Types 34 and 35

Types 34 and 35

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A 5 yo male child had onset of cough, nasal congestion, fever, and sore throat for 2 days, you suspect that the etiologic agent is an Adenovirus, which specific group of Adenoviruses does the etiologic agent belong? *
Group E
Group C
Group B
Group A

Group C

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Major sites of Parvovirus replication include: *
fetal bone marrow
ALL blood cells
fetal liver
CNS

fetal liver

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Which among these blood type is at risk for acquiring Parvovirus B19 infection: *
Duffy
Lewis
P
ABO

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Principal targets for human B19 parvovirus? *
Immature cells in the erythroid series
Mature RBC
Platelets
Immature Leukocytes

Immature cells in the erythroid series

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Mode of Transmission of Parvovirus: *
Vertical
Parenteral
Respiratory
All are correct

Respiratory

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a 30 yo G2P1 (1001) 19 weeks Age of Gestation, mother came into your clinic, showing signs and symptoms of Parvovirus B19 Infection, what is the probable outcome of her pregnancy: *
Fetal demise
All are correct
Healthy baby
Baby will produce antibody against B19

Fetal demise

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Treatment of Adenoviruses infection: *
None
Remdesivir
Azithromycin
Cefuroxime

None

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Property/ies of Adenoviruses: *

Replication in the cytosol
RNA, linear, 26–45 kbp, protein bound to termini, infectious
With envelope
Adenoviruses replicate well only in cells of epithelial origin.

Adenoviruses replicate well only in cells of epithelial origin.

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The following are commonly used urinary antiseptics:
Chloramphenicol
Ampicillin
Nalidixic acid
Metronidazole

Nalidixic acid

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TRUE of Erythema Infectiosum (Fifth Disease): *

The incubation period is usually 4-5 weeks but may extend to 6 weeks.
Specific IgM antibodies appear about 15 days postinfection.
This erythematous illness is most common in children of early school age and occasionally affects adults. Fever and mild constitutional symptoms may accompany the rash, which has a typical “slapped cheek” appearance
All are correct

This erythematous illness is most common in children of early school age and occasionally affects adults. Fever and mild constitutional symptoms may accompany the rash, which has a typical “slapped cheek” appearance

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These serotypes of Adenoviruses are etiologically associated with infantile gastroenteritis *
Serotypes 15 and 41
Serotypes 40 and 41
Serotypes 10 and 11
Serotypes 30 and 32

Serotypes 40 and 41

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Cytomegalovirus affects the organs in latent infection except *

Kidneys
Glands
Lymphoid tissue
Neurons

Neurons

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The common name of Human Herpes 8 is *

Epstein-Barr
Herpes Simplex
Kaposi sarcoma
Varicella-zoster

Kaposi sarcoma

The assembly of the virus particle from the manufactured components is a complex process. Some of the particles are released from the cell by budding, but the majority of poxvirus particles *

transfer to another cell for further replication
mutate to a more virulent virus
remain within the host cell
die

remain within the host cell

Primary host of ORF Virus: *
Cow
humans
rodents
Sheep

Sheep

Replication site of Poxvirus: *
Mitochondria
Golgi apparatus
Cytoplasm
Nucleus

Cytoplasm

The portal of entry of variola virus: *
break in the skin
ingestion
mucous membranes of the upper respiratory tract
All are correct

mucous membranes of the upper respiratory tract

when the variola virus enters the body, all of the following will take place EXCEPT: *
NO EXCEPTION
transient viremia and infection of reticuloendothelial cells throughout the body xxx
primary multiplication in the lymphoid tissue draining the site of entry xxx
a secondary phase of multiplication in those cells, leading to a secondary, more intense viremia; and the clinical disease

NO EXCEPTION

The incubation period of variola (smallpox) *
1 month
1-2 days
10-14 days
1-5 days

10-14 days

The etiologic agent of contagious pustular dermatitis or sore mouth infection. *
Tanapox
Molluscum contagiosum
Variola
Orf virus infection

Orf virus infection

which of the following elements prevents inactivation of Poliovirus? *
Iron
sodium deoxycholate
Magnesium
ether

Magnesium

Primary multiplication site of Poliovirus? * Intestine Brain Mouth blood

Intestine

Most common manifestation/form of Poliovirus infection? * The predominating complaint is flaccid paralysis resulting from lower motor neuron damage. A recrudescence of paralysis and muscle wasting has been observed in individuals decades after their experience with paralytic poliomyelitis. stiffness and pain in the back and neck. The disease lasts 2–10 days, and recovery is rapid and complete. complete. The patient has only a minor illness, characterized by fever, malaise, drowsiness, headache, nausea, vomiting, constipation, and sore throat in various combinations. Recovery occurs in a few days

The patient has only a minor illness, characterized by fever, malaise, drowsiness, headache, nausea, vomiting, constipation, and sore throat in various combinations. Recovery occurs in a few days

They are the most commonly recovered agents from people with mild upper respiratory illnesses. They are usually isolated from nasopharyngeal secretions but may also be found in throat and oral secretions. * Rotaviruses Rhinoviruses Poxvirus Vaccinia virus

Rhinoviruses

Rhinoviruses grow better at what temperature? * 18C 22C 28C 33C

33C

The natural reservoir of cowpox: * human fox rodent cattle

rodent

How to diagnose Molluscum contagiosum? * Electron Microscopy Clinical PCR Culture

Clinical

Natural host of Tanapox virus? * Sheep Monkey Cow Human

Monkey

The picornavirus replication cycle occurs in the: * Endoplasmic Reticulum Nucleus Cytoplasm of cells Golgi apparatus

Cytoplasm of cells

TRUE of poliovirus: * Most strains will infect monkeys when inoculated directly into the brain or spinal cord Poliovirus does not require a primate-specific membrane receptor for infection, and the absence of this receptor on the surface of nonprimate cells makes them virus resistant. ALL are TRUE There are three antigenic types of polioviruses based on epitopes found in the P1, P2, and P3 proteins

Most strains will infect monkeys when inoculated directly into the brain or spinal cord

A 20 yo female present with abrupt onset of fever and stabbing chest pain which is preceded by malaise, headache, and anorexia. Based on the history, the chest pain was noted for more than a week now. There is also associated abdominal pain. What do you think is the etiologic agent? * group D coxsackieviruses group C coxsackieviruses group A coxsackieviruses group B coxsackieviruses

group B coxsackieviruses

The incubation period of coxsackievirus infection ranges from: * 14 days 2-9 days 1-2 days 1 month

2-9 days

emerged as a cause of severe hand-foot-and-mouth disease, sometimes followed by nail shedding * group B coxsackieviruses Coxsackievirus A6 coxsackievirus A16 group C viruses

Coxsackievirus A6

chief cause of acute hemorrhagic conjunctivitis: * group B coxsackieviruses Coxsackievirus A6 Enterovirus 70 coxsackievirus A16

Enterovirus 70

sequelae of acute hemorrhagic conjunctivitis: * sepsis None Blindness cataract formation

None