Bone 2

Question 1

What is developmental orthopaedic disease?

Answer 1

Group of diseases involving musculoskeletal problesm
multifactorial aetiology
Disturbance in development- cartilage, bone

Question 2

What is the Articualr epiphyseal cartilage complex? and what the of ossification occurs here?

Answer 2

Endrochondral ossification

AECC is the articular cartilage. in growing animals growth is much the same as in growth plate (physics)

Question 3

Growing bone, where does primary and secondary ossification occur?
If abortive foetus what would be see

Answer 3

Primary = in diaphysis
secondary in epiphysis

Abortive foetus would see primary centres of ossification nice reddish colour
cartilage = white, unossified as secondary centres not kicked in yet

Question 4

bone vs cartilage on XRAY

Answer 4

Bone = radio opaque = white
cartilage = radiolucent = cannot see

Question 5

Growth plate anatomy- list the diff sections

Answer 5

1. resting cartilage
2. proliferative cartilage
3. hypertrophic cartialge
4. calcification - BV migrate in to reabsorb cartilage matrix
5. Ossification

Question 6

Where could endrochondral ossification go wrong

Answer 6

Physeal growth plate - uneven growth
or
Articular-epiphyseal cartilage complex (AECC) - diseases affecting joints

Question 7

give examples of Physeal growth plate malfunction

Answer 7

Abnormal deposition of matrix
Abnormal mineralisation of cartilage
Poor conversion to bone
Retention of cartilage: biggy. Not huge problem but manifests in horses with osteochondritis dysicans

result in: slow growth and uneven growth

Question 8

Give examples of articular epiphyseal cartilage complex diseases

Answer 8

Abnormal deposition of matrix
Abnormal mineralisation
Retention of cartilage – more of a issue than at a growth plate

Result:
Slow growth – changes angle of bone growth
Uneven growth
Cartilage flaps- uneven retention = osteochondrosis or osteochondritis dessicans