cardioresp Flashcards

1
Q

How do we detect where heart murmur is?

A

Point of maximal intensity (location) of heart murmurs

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2
Q

Listed to heart

loudest at left apex. what valve?

A

Left Apex:

- Mitral valve

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3
Q

Listed to heart

loudest at Best base what valve?

A

Left Base:

  • Pulmonic valve
  • Aortic valve
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4
Q

Listed to heart

loudest at Left Cranio-Dorsa what valve?

A
Left Cranio-Dorsal:
Patent ductus
  arteriosus (PDA)
Right side of chest:
-Tricuspid valve      	(apex)
-VSD loudest on R (cranio-sternal)
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5
Q

Listed to heart

loudest at Right side of chest apex what valve?

A

Right side of chest:

-Tricuspid valve (apex)

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6
Q

Listed to heart

loudest at Right side of chest craniotomy sternal, what valve?

A

-VSD loudest on R (cranio-sternal)

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7
Q

Not 100% sure if dog’s backwards heart failure is right or left sided
what is a way to check if right?

explain it

A

Hepato jugular reflex
Gentle pressure on the caudal abdomen causes increased distention / pulsation of the jugular veins:
Inc Venous return by caudal vena cava to right atrium, if RA failing = reduced drainage from cranial VC = jugular more distension

sign of increased right sided filling pressure (more blood returning to heart via caudal vena cava will lead to head and neck blood damming back).
Useful test

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8
Q
Puppy comes in with a heart murmur
what type is it?
rough age of pup?
grade on murmur
what is it due too?
A

Age:
Young puppies (and kittens), should Diminish with growth
Disappear by 16 – 20 weeks old
Grade and sound?
Usually < grade 3/6
Low pitches, left basular, musical, less loud as pup grows and disappears by 20 weeks

Why?
Due to change from foetal to adult haemoglobin
Can be difficult to distinguish from congenital heart disease
Watchful monitoring or investigate depending on how loud and purpose of dog
Loud often not innocent

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9
Q

Need vagomimetic? what drug

A

Digoxin

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10
Q

Need positive inotrope?

A

Pimobendan

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11
Q

Dog with oedema. What do and drug use first

A

IF pulmonary = Thoraco-centesis immediately!

If ascites don’t need to drain as not life threatening
DIURETICS = life saving
Furosemide = loop diuretic

Then ACE inhibitor - monitor renal function

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12
Q

How can owner monitor if need to inc or dec fursomide drug conc to tackle oedema?

A

Monitor sleeping or resting rest rate
reduce dose of F is RR stable
inc dose if RR inc

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13
Q

Side affects furosemide

A

Pre-renal azotaemia​

Hypokalaemia​ - may need to supplement K+

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14
Q

Furosemide no longer works and highest dose possible…

A

Use ACE inhibitors to improve cardiac function
GIT oedema consider parenteral admin
additional diuretics?
Substitute with more potent loop diruetic torasemide

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15
Q

Role of ACE inhibitors

A

Angiotensin-convertin enzymes

Balanced vasodilators​
Reduce aldosterone release, so reduced Na+ &H2O retention​
Prevent Angiotensin II mediated myocardial fibrosis and remodelling ​
Permissive anti-adrenergic effects​
Reduce vasopressin release​
Reduce endothelin release​
Increased levels of bradykinin & vasodilatory prostaglandins = help with renal function​
Prevent glomerular capillary hypertension ​

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16
Q

Side effects ACE inhibitors

A

Hypotension​
Renal impairment​
Hyperkalaemia​
Anorexia, diarrhoea, vomiting etc. ​

so monitor blood pressure, renal and electrolytes

17
Q

Name 2 balances vasodilators and what they do on pr and afterlaod

A

ACE inhibitors​
Pimobendan​
Reduce preload, afterload, improve function

18
Q

Pimobendan

A

ositive inotrope by inc sensitivity to Ca = more actin myosin interaction​
= inc contractility​

19
Q

dog with atrial fibrillation what drug?

A

DIGOXIN
negative chronotropy without negative inotropy
it is a vagomimetic

enhances vagal tone and reduces sympathetic drive by: ​

- Direct stimulation of vagal centres in CNS​
- Sensitizes baroreceptors to changes in BP​
- Enhances cardiac pacemaker responses to ​
acetylcholine (ACh). ​
These effects result in: ​
- slowed rate of discharge of SAN​
- slows conduction through AVN​
- increases refractory period in AVN​

20
Q

Optimal treatment of CHF in dogs with MCD air DCM

A

SPAF

Furosemide​
ACE-I (benazepril)​
Pimobendan – real improtant​
Spironolactone​
All counteracting RAAS
21
Q

Dog with CHF MVD or DCM but cannot afford SPAF

A

furosemide (£) and Pimobendan (positive inotrope