Bone biology (Yr 3)

Question 1

what are the cells seen in bone?

Answer 1

osteoblasts, osteocytes, osteoclasts

Question 2

what is the function of bone?

Answer 2

skeletal support (movement/structure)
protection (thorax, pelvis…)
haematopoesis (marrow)
regulate mineral homeostasis (PTH)
fat storage

Question 3

what are the three sections of long bones?

Answer 3

diaphysis
metaphysis
epiphysis

Question 4

what are the two types of bone?

Answer 4

cortical
cancellous (spongey shock absorbing)

Question 5

what is the process by which bone increases in length?

Answer 5

endochondral ossification

Question 6

where does endochondral ossification occur?

Answer 6

growth plates

Question 7

what are the two ways bone grows?

Answer 7

endochondral ossification
intramembranous ossification

Question 8

how do bones remodel to increased load?

Answer 8

micrombdelling of trabecular bone leading to increased thickness of the trabeculae

Question 9

what is the function of bone remodelling?

Answer 9

replace damaged bone
prevent accumulation of fatigue damage (stress fracture)