Bordetella Flashcards
(28 cards)
This organism has bipolar metachromatic granules
B pertussis
Describe bordetella pertussis
RENAN
ROD ENCAPSULATED NEGATIVE AEROBIC NONMOTILE
Give some enriched media for b pertussis
Bordet-gengou
Potato-blood-glycerol agar
B pertussis are grown in charcoal containing media
True
B parapertusis are oxidase positive and urease positive
False. Urease positive. Negative oxidase
B bronchoseptica are both urease and oxidase positive
True
This bordetella sp causes subclinical infxn and has a silent copy of the pertussis toxin gene
B parapertusis
This sp of bordetella causes infxns in animals
B bronchoseptica
The highly infective stage of pertussis
Catarrhal stage
Catarrhal has the highest amount of bacterial load
Catarrhal
What phase are toxins produced and liberated
Produced - catarrhal
Liberated - paroxysmal
IPCPC q 7-10days 1-2 2-4 3-4
This condition prediminates in infants
Whoop - convulsions
This predominates in older children and adults
Paroxysmal coughing
Fatal complication of pertussis though rare
Encephalitis
Blood is invaded with pertusis
False
Death usually occurs in the 3rd year of life
Under 1
Cbc manifests leukemoid rxn
Pertusis
Serologic testing is diagnostic of pertusis
No, antibodies do not increase until 3rd wk of illness. Already in paroxysmal. Abx not effective
Vancomycin is given for pertussis
False. Erythromycin
This toxin causes ischemia leading to tracheal necrosis
Dermonecrotic toxin
This virulence factor mediates adhesion to ciliated epithelial cells
Filamentous hemagglutinin
This toxin acts with dermonecrotix toxin in causing tracheal necrosis
Tracheal toxin
This toxin causes pertussis by inhibiting DNA synthesis inhibiting non ciliated cell differentiation
Tracheal toxin
Tracheal toxin is a peptidolglyan like molecule
True