Bordetella Flashcards

(28 cards)

0
Q

This organism has bipolar metachromatic granules

A

B pertussis

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1
Q

Describe bordetella pertussis

A

RENAN

ROD
ENCAPSULATED
NEGATIVE
AEROBIC
NONMOTILE
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2
Q

Give some enriched media for b pertussis

A

Bordet-gengou

Potato-blood-glycerol agar

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3
Q

B pertussis are grown in charcoal containing media

A

True

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4
Q

B parapertusis are oxidase positive and urease positive

A

False. Urease positive. Negative oxidase

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5
Q

B bronchoseptica are both urease and oxidase positive

A

True

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6
Q

This bordetella sp causes subclinical infxn and has a silent copy of the pertussis toxin gene

A

B parapertusis

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7
Q

This sp of bordetella causes infxns in animals

A

B bronchoseptica

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8
Q

The highly infective stage of pertussis

A

Catarrhal stage

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9
Q

Catarrhal has the highest amount of bacterial load

A

Catarrhal

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10
Q

What phase are toxins produced and liberated

A

Produced - catarrhal
Liberated - paroxysmal

IPCPC q
7-10days
1-2
2-4
3-4
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11
Q

This condition prediminates in infants

A

Whoop - convulsions

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12
Q

This predominates in older children and adults

A

Paroxysmal coughing

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13
Q

Fatal complication of pertussis though rare

A

Encephalitis

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14
Q

Blood is invaded with pertusis

A

False

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15
Q

Death usually occurs in the 3rd year of life

16
Q

Cbc manifests leukemoid rxn

17
Q

Serologic testing is diagnostic of pertusis

A

No, antibodies do not increase until 3rd wk of illness. Already in paroxysmal. Abx not effective

18
Q

Vancomycin is given for pertussis

A

False. Erythromycin

19
Q

This toxin causes ischemia leading to tracheal necrosis

A

Dermonecrotic toxin

20
Q

This virulence factor mediates adhesion to ciliated epithelial cells

A

Filamentous hemagglutinin

21
Q

This toxin acts with dermonecrotix toxin in causing tracheal necrosis

A

Tracheal toxin

22
Q

This toxin causes pertussis by inhibiting DNA synthesis inhibiting non ciliated cell differentiation

A

Tracheal toxin

23
Q

Tracheal toxin is a peptidolglyan like molecule

24
This exotoxin cholera like is responsible for paroxysmal coughing
Pertussis toxin or pertussigen Di porke p toxin ay ngkakacause ng pertussis
25
This virulence factor is activated by calmodulin. Increases CAMP, increase h20, increase secretions
Adenylate cyclase toxin
26
An oligopeptide
Pertussigen
27
Promotes lymphocytosis and increases igE and LPS
Pertussigen