Corynebacteria. Listeria

Question 0

In what dye are the metachromatic granules highly stained

Answer 0

Aniline dye

Question 1

Give the shape of corynebacterium

Answer 1

Rod, in parallel or acute angle with irregular swelling at one end

Question 2

What do u call the irregular swelling in one end of coryne

Answer 2

Babes-Ernst bodies

Question 3

True or false. C. Diph are resitant to heat and killed by drying

Answer 3

False. Killed by heat. Resistant to drying

Question 4

How long can they stay in dust? C. Diph

Answer 4

102 days

Question 5

C diph grows best on ——- environment

Answer 5

Anearobe at 37

Question 6

They can be found where? C diph

Answer 6

Fresh and salt water soil and air

Question 7

Their characteristic on blood agar

Answer 7

Small, granular, gray, irregular edges

Question 8

Reduced tellurite is positive of what

Answer 8

Staph, strep, coryne

Question 9

Give the rxn in tellurite agar

Answer 9

Brown to black with halo

Question 10

This medium grows more coryne than other org

Answer 10

Loeffler

Question 11

Other name for potassium tellurite

Answer 11

Modified tinsdale

Question 12

True or False. All coryne subtypes are toxigenic.

Answer 12

False

Question 13

What causes toxigenicity in c diph

Answer 13

Phage gene

Question 14

Invasiveness due to

Answer 14

Bacterial gene

Question 15

Resistant drugs to listeria

Answer 15

Fluoroquinolones

Cephaloaphorins

Question 16

DOC for listeriosis

Answer 16

Ampicillin plus gentamicin

Erythro. Cotri

Question 17

Diphteria is spread via

Answer 17

Droplet and contact trans

Question 18

It desires low iron content for growth.

Answer 18

C diph

Question 19

What level of iron does c diph growth is optimal and suppressed

Answer 19

Optimal 0.14

Supp 0.5

Question 20

Diph toxin is heat labile. True or false

Answer 20

True

Question 21

Which fragment of diph toxin binds to CD9 and HBEGF

Answer 21

Fragment b

Question 22

This inhibits polypeptide chain elongation via ef 2

Answer 22

Fragment a

Question 23

This is responsible for the neurotoxic and necrotizing effect of diph toxin

Answer 23

Abrupt cessation of protein synthesis

Question 24

This is manifested as cervical adenitis and submandibular edema

Answer 24

Bullneck

Question 25

Diphteria incubation period

Answer 25

2-6 days

Question 26

How many weeks does the bcteria persist in untreated infxn

Answer 26

6 weeks

Question 27

With treated diph, they become less comm at what day/week

Answer 27

Less than 4 days

Question 28

Most common loc of virulence

Answer 28

Upper respi tract

Question 29

Exudates in nasal

Answer 29

Serosanguinous or seropurulent

Question 30

Doc for diph

Answer 30

Pen and ery x 14 days

Question 31

What co existing org is also killed with ery and pen?

Answer 31

Strep

Question 32

Elimination is documented when?

Answer 32

24 h post last say of meds. 2 cons negative, 24 h apart

Question 33

Tellurite can have definite colonies in how many hours?

Answer 33

36-48h

Question 34

Loeffler slant yields microbe in how many hours?

Answer 34

12-18h

Question 35

What does negative culture but positive PCR means?

Answer 35

Positive

Question 36

This test shows a precipitation line post 48hours at 45 degrees

Answer 36

Mod elek test

Question 37

Used to detect tox gene

Answer 37

Pcr

Question 38

What must be done prior to diph antitoxin administration? When must it be done?

Answer 38

Skin test. Same day of dx.

Question 39

Cutaneous diph are treated for how many days?

Answer 39

10 days and cleanse with soap and water

Question 40

Where is the primary lesion in diph

Answer 40

Throat

Question 41

Prophylaxis for diph

Answer 41

Ery x 10 days IM Pen G, 1 dose Active vaccination

Question 42

When does heart problem occurs?

Answer 42

When respi symptoms are improving at 2-3 weeks

Question 43

Neuro prob occurs when and involves what.

Answer 43

Soft palate, pharyngeal wall. Sensory and motor nerve.

Question 44

This coryne doesnt produce toxins.

Answer 44

Diphtheroids

Question 45

Diphteroids asso with cath infxns

Answer 45

C striatum

Question 46

Causes pharyngitis

Answer 46

C. Haemolyticum

Question 47

Causes skim ulcers

Answer 47

Bovis. Haemolyticum. Ulcerans

Question 48

Causes bacteremia and sepsis

Answer 48

Xerosis. Group D2, E, JK. Pyogenes. Bovis

Question 49

This virulence actor hydrolyses sphingomyelin promoting spread of what org

Answer 49

Phospholipase D. Diphtheroids

Question 50

This causes alkalinization of urine and leads to struvite formation

Answer 50

Urease

Question 51

Doc for diphteroids

Answer 51

PM FR Pen. Macrolide. Fluoro. Rifam

Question 52

This culture media is used for listeria

Answer 52

Mueller Hinton agar

Question 53

This non spore forming, gram positive have peritrichous flagella

Answer 53

Listeria

Question 54

Motile and esculin positive non spore forming gram positive

Answer 54

Listeria

Question 55

What do u call the movement of listeria

Answer 55

Tumbling end over end motolity at 22-28

Question 56

True or false. Listeria grows in 4degree, low ph and high salt

Answer 56

True

Question 57

This virulence factor promotes phagocytosis. Cell surface protein

Answer 57

Internalin

Question 58

This promotes formation of filopods which are elongates protrusions

Answer 58

ActA

Question 59

This promotes the lysis of phagolysosome.

Answer 59

Listeriolysin O.

Question 60

True or false. This organism can move from cell to cell without being exposed to abs

Answer 60

True

Question 61

What happens to immunocompetent patients with listeria

Answer 61

Febrile gastroenteritis. Self limiting

Question 62

Occurs in immunocom with listeria

Answer 62

Meningo and bacteremia

Question 63

Disseminated form of listeria

Answer 63

Granulomatosis infantiseptica

Question 64

This listeria serotype causes late onset syndrome

Answer 64

Serotype ivb