brain learning and motivation: neural communications Flashcards

1
Q

typical neuron structure

A

neutrons are basic building blocks of nervous system

nucleus
cell membrane
dendrites
sona *cell body
Myelin sheath
node of ranvier
axon
axon terminals
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2
Q

informaion passing through neutrons

A

information passes down neutron by electrical impulse

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3
Q

information is transmitted within neutrons

A

through axonal conduction

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4
Q

information transmitted between neutrons

A

through synaptic transmission

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5
Q

how they communicate

A

the neuron generates an electrical impulse that travels down the axon and into the axon terminals

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6
Q

3 main neuron types

A

sensory
motor
interneuron

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7
Q

purkinje neutron found by

A

costandi

Ramon V Cajal in 1899

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8
Q

neuron structure: soma

A

the ell body

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9
Q

neuron structure: dendrites

A

specialised receiving units that collect messages from neighbouring neutrons and send them on to the cell body

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10
Q

neuron structure: Axon

A

cunducts electrical impulses away from cell body to other neutrons muscles or glands

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11
Q

neuron structure: Myelin Sheath

A

series of fatty wrappers formed by Glial cells
surrounds axons of neutrons that communicate over long distances in nervous system
allow fast propagation of action potentials along those axons

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12
Q

MS

A

De-Myelination occurs

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13
Q

neuron structure: nodes of Ranvier

A

Gaps between the Glial cell wrappers of Myelin Sheath around axons
nodes are crucial to the speed of electrical impulses along Myelinated axons
electrical signal is slow even in Myelinated neutrons its around 1-91m per sec

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14
Q

the ways in which neutrons pass information

A

electrical impulses

chemistry

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15
Q

Myelinated neurons appearance

A

white matter
whitish appearing particles and paths in the brain
composed of Myelinated neurons in particular Axons

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16
Q

gray matter

A
the absence of myelination
gray matter is:
Dendrites
cell bodies
unMyelinated axons
...these are the nervous systems microcircuitry
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17
Q

Glial cells

A

act as a guide wire for growing neurons
provide a supportive scaffolding for mature neutrons
form Myelin Sheath and blood brain barrier

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18
Q

the blood brain barrier

A

protects the brain from:
noxious substances
some drugs

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19
Q

blood vessels in brain

A

selectively permeable barrier
have a protective lining
allows in nutrients but keeps out toxious substances
prescription drugs for brain conditions must be able to pass through barrier

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20
Q

Neuron communication: Axon membrane

A

Axon membrane is semi permiable so some chemicals can pass through freely others cat

When Axon membrane is stable there is an excess of positive ions on outside making a negative charge difference

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21
Q

recording voltage within a neutron

A

an electrode is inserted into axon
the other records from Axons outside
at rest a -70 millivolt different ewill be detected
at firing the voltage will shift slightly before returning to resting voltage

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22
Q

Neuron communications: electrical communications and voltage changes

A

when membrane is stimulated it deeplarises
and sodium ion channels open
this leads to an action potential
ion movement leads to an excess of positively charged particals inside the membrane
this produces a positive voltage swing
the excitation spreads leading to propagation of the action potential along the axon
immediately there is a refraction period
potasium channels open causing hyper polarisation

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23
Q

electrical communications: hyperpolarisation

A

more negatively charged inside than the resting potential

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24
Q

electrical communications: duing refractory period

A

cells are less sensitive to stimulation than they are normally

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25
electrical communications; return to resting potential
there are pumps that actively use energy to move sodium ions out of the neutron for every two potassium ions it puts in At rest, again there are rela;vely more sodium ions outside the neuron and more potassium ions inside that neuron
26
electrical communications: sequence of events of action potential
neuron membrane is disturbed sodium channel opens and sodium floods in when voltage reaches -55 the neutron fires sending a wave of electrical impulse along the neutron sodium channels close and potasium opens reversing depolarisation potasium channels close ack to resting potential
27
electrical communications: propagation is muc faster if ...
axon is myelinated Depolariza$on proceeds down the axon by a number of skips or jumps because ion cannels only open at the nodes of ranvier
28
electrical communications: action potential and the all o none law
Once it’s launched, further increases in s;mulus intensity have no effect on its magnitude.
29
interneural communication
``` at axon terminal the electrical signal causes the release of specialised chemicals these chemical (neurotransmitters) travel across synapse to next neutron ```
30
chemical communications: synapse
the unction between two neutrons consisting of the presynaptic membrane post synaptic membrane and synaptic cleft between them
31
chemical communications: neurotransmitters
make communication between two neutrons possible by: crossing synapse latching onto receptors on postsynaptic cel triggering a response in the ell some neurotransmitters are deactivated shortly after being discharged, this is done by "clean up: enzymes they are also more commonly reused by a process called synaptic repute different kinds of neuro transmitters
32
chemical communications:lock and key model
proposes that: transmitter molecules will affect the postsynaptic membranes if the molecules shape fits into certain synaptic receptor molecules
33
chemical communications: posysynaptic transmission
depending on the type of receptor that is activated the attachment of the neurotransmitters either: excites or inhibits the generations of an action potential in the postsynaptic cell
34
chemical communications; excitatory/inhibitory
the resulting chemical changes are graded and can be either excitatory or inhibitory whether the neutron fires depends on the sum of these effects
35
chemical communications: neurotransmitters and drugs
can impede or enhance the action of neurotransmitters
36
Drugs: agonists
enhance efect of a neurotransmitter can: increase release of neurotransmitters, amphetamine doe this block reputake of neurotransmitters this happens with prosaic and cocaine can mimic specific neurotransmitters by binding to postsynaptic receptors and either activating them or increasing effects of neurotransmitters main effect of nicotine
37
drugs:antagonist
impede effect of neurotransmitter can: block release of neurotransmitters, main effect of AMPT destroy neurotransmitters in synapse, mimic a spacific neurotransmitter binding to postsynaptic receptors enough to block any more neurotransmitter binding, main effect of propanelol (beta blocker) and halloo (antipsychotic drug)
38
amphetamine
``` agonist increases the release of neurotransmitters in particular: dopamine neophhephrine ```
39
cocaine and prosak
agonist | blocks repute of neurotransmitters
40
nicotene
agonist mimics spacific neurotransmitters and either: activates them or increases neurotransmitters effects
41
AMPT
antagonist | blocks release of neurotransmitters
42
propranalol and Hadol
mimic a spacifi neurotransmitter and bind to postsynaptic receptor enough to stop further binding
43
neurotransmitters: seratonin
``` usually inhibitory involved in many mechanisms of: sleep arousal aggression mood appetite overproduction causes OCD ```
44
: selective seratonin reuptake inhibitors
reduce uptake of the neurotransmitter from the synapse prosak Zolott and Paxil: increase serotonin turnover in brain and find wide use as treatments for depression, obsessive compulsive disorder etc...
45
neurotransmitters: GABA
gama-amibo butyric acid most widely distributed inhibitory transmitter in central nervous system implicated in anxiety disorders and depression
46
alcohol and synapses
``` alcholo has multiple effects on neutrons italters: neutron membranes ion channels receptors enzymes ``` ``` it bind directly to receptors for: acetylcholine seratonin GABA glutamide ```
47
alcohol and the GABA receptor
alcohol binds to GABAreceptors and amplifies the hyperpolarization effect of GABA neutron activity is further diminished this accounts for some of the sedative affects of alcohol
48
hyperpolarization
occurs when the strength of an electric field across a cell membrane increases
49
if the changes in the negative potential do not reach the -50mv action potential they are said to be...
graded potentials
50
action potentials occur in...
axons dendrites cell bodies
51
adrenal glands secrete hormones that regulate the ...
metabollic processes
52
the key mechanism of the action potential is...
the action of the sodium and potassium channels in the cell membrane
53
when sodium ions flood into cell this is...
depolarisation
54
overactivity of serotonin is ascociated with
obsessive compulsive disorder
55
Sperrys ecperiment
selected participants who were right handed show localisation of the brain and that verbal abilities were located on the left hemisphere
56
researchers use these kinds of brain damage to investigate the function of different areas of the brain
``` degenerative disead tumour vascular infectious disease trauma epilepsy ```
57
the association cortex is involved in...
many important mental function such as: perception langage thought
58
why researcher might use an EEG
to explore the possibility of abnormal activity within the brain
59
amphetamine increases the activity of ...
Dopamine | Noephephrine
60
for a neuron to fire theorised must be...
+40 mv compared to the outside
61
the brain is made up of...
fluid fat protein
62
an inhibitory neurotransmitter causes...
negative chloride ions from the exterior to flow in | positive potasium ions t flow out of the neuron
63
the neurotransmitter endorphin is the best known...
neuromodulator
64
synaptic vesicles are...
chambers within the icon terminals where neurotransmitter molecules are stored
65
example of a neuropsychological test
trail making test used to test memory and planning
66
james olds 1953 study...
dopamine produced rewarding behaviour in rats