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Flashcards in Breast Deck (35):
1

___________ (off 2nd intercostal nerve) sensation to medial arm; can or cannot sacrifice?

Intercostobrachial nerve; CAN sacrifice

2

_________ nerve to serratus anterior, injury= ______

Long thoracic nerve; winged scapula

3

_______ nerve to latissimus dorsi, injury= ________

Thoracodorsal nerve; weak arm adduction/pull ups

4

_________ nerve to pec major and minor

Medial pectoral nerve

5

______ nerve to pec minor only

lateral pectoral nerve

6

_______: Valveless vertebral veins, allow direct mets to _____

Batson's plexus; mets to spine

7

Poland syndrome: _______, _______, ______

amastia, hypoplastic shoulder, no pectoralis

8

Mastodynia Rx?
____, ____, ___, ____
____ not useful

danazol; OCP; evening primrose oil; tamoxifen (?); vit E not useful

9

______: thrombophlebitis of superficial vein of breast. Cord like mass laterally; Rx: ______.

Mondor's disease; rx NSAIDs

10

Breast Cancer T sizes:
T1 ____
T2 ____
T3 ____
T4 ____

T1 < 2cm
T2 2-5cm
T3 >5cm
T4 skin or chest wall involvement

11

breast ca 'grave signs' = ______, ______

peau d'orange, inflammation

12

Breast cancer N stuff
N1 ______
N2 ______
N3 ______

N1 positive ax nodes
N2 matted or fixed nodes
N3 internal mammary nodes

13

Breast cancer stages:
Stage I ____
Stage II _____ or ____
Stage III __ or __
Stage IV ____

I: T1
II: up to T2N1 or T3N0
III: T4 or N2
IV: Mets (includes supraclav node; unlike lung CA)

14

Breast mets: ___, ____, _____

bone, lung, brain

15

_______: a marker for breast CA, implies worse prognosis. _______ now available for Rx.

Her 2 neu; Herceptin

16

___, ___, ____ all indicate worse prognosis in breast ca

erb b 2, p 53, cathepsin

17

1 cm tumor is around how old?

~5 year old

18

_______ reduces risk 50% in high risk bu inreases risk of ______ cancer and ____.

Tamoxifen; endometrial cancer, DVT

19

_________ raises risk x 4 for breast cancer

atypical hyperplasia (only finding in fibrocystic that increases risk)

20

ER +/- PR +/- ____; is better than ER PR __ which is better than ER PR __ which is better than ER PR __

ER+PR+ > ER-PR+ > ER+PR- > ER-PR-

21

DCIS ____% develop invasive carcinoma; is or is not a precursor?

50%; is a precursor

22

DCIS Rx
usually _____
high grade/large tumor/poor margins _____

usually lumpectomy + RT;
mastectomy for high grade, etc.

23

___% of DCIS recurrence is invasive

50%

24

LCIS ____% develop invasive carcinoma (either breast)

30-40%; is a marker of risk

25

Rx options for LCIS
___, _____, ____

nothing, tamoxifen or bilateral mastectomy

26

Comedo breast cancer:
Multicentric or localized? ____
Rx? ____
Good or poor prognosis? ___

Multicentric; mastectomy; poor

27

Paget's disease of the breast:
____ lesions on the ___ (part of breast)
There is underlying ____ or ____

eczematous lesions on nipple; underlying DCIS or Ductal Ca

28

Cystosarcoma Phyllodes or 'Phyllodes tumor'
____% malignant? ___
Large or small? ____
Rare or common nodal mets? ____
Spread? Heme/lymph ____

10% malignant; large; rare nodal mets; hematogenous

29

Rx for cystosarcoma phyllodes or "Phyllodes tumor'

wide local excision, rarely mastectomy, NO axillary node dissection

30

BRCA: ___% have cancer by age 70

85%

31

BRCA1 a/w ___ cancer (____%)

ovarian cancer; 50%

32

BRCA2 a/w ______

male breast cancer

33

Indications for RT after mastectomy:
___ nodes
____ involvement
_____

>4 nodes; skin or chest wall involvement; positive margins

34

Stewart Treves: _________ in __________ limb. Presents with _______ on arm.
Occurs ______ (time) s/p ______

lymphangiosarcoma in lymphedematous limb; purplish mass on arm; 10 years s/p MRM

35

_____: No risk of CA. #1 cause of bloody nipple discharge (although 1/2 are serous)

Intraductal Papilloma