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Flashcards in Medicines Deck (19):
1

Ketamine: increase or decrease...
Cardiac work? o2 use? Secretions? BP? Respiratory Depression? Hallucinations?

Increases cardiac, work o2 use, secretions, BP.
No respiratory depression.
Yes hallucinations.

2

Methoxyfluorane has _ toxicity

renal toxicity

3

Halothane has _ toxicity

hepatotoxic

4

_ is a depolarizing agent, generalized contractions, hyperkalemia in burn patients, fast on/off; risk of aspiration, glaucoma

Succinylcholine

5

_ (drug) prolongs neuromuscular blockade

Clindamycin

6

_ (drug) should be avoided in patients on MAOIs

Demerol

7

Octreotide:
long/short acting _ analog/agonist

long-acting somatostatin analog

8

Reglan: aka _
mech?
incr/decr LES tone?
incr/decr gastric motility?

metoclopramide; DA blocker; increases LES tone and gastric motility

9

Ompeprazole:
mech: _
aossicated w/ _ in rats
Evidence of carcinogenesis in humans?

mech: blocking Na/H ATPase
a/w enterochromaffin hyperplasia in rats
NO evidence of carcinogenesis in humans

10

Digoxin:
Mech: _ (action-enzyme) to increase _ (effect)
Slows/speeds up AV conduction?
Increases O2 consumption? (yes/no)
Associated with _ (side effects)

glycoside; inhibits Na-K ATPase to incr Ca in heart
SLOWS AV conduction
Inotrope but DOES NOT incr o2 consumption
A/w ischemic gut, decr splanchnic flow, avoid hypokalemia

11

Amrinone:
Mech?
Incr/Decr CO?
Incr/Decr SVR?

Phosphodiesterase inhibitor; inotrope
Incr CO
Decr SVR

12

_ and _ (drugs): 'medical adrenalectomy'

metyrapone and aminoglutethimide

13

_ (drug): 'medical orchiectomy'

Leuprolide

14

Vasopressin:
incr/decr splanchnic blood flow?
Useful in _ (disease).
Give with _ to avoid angina

reduces splanchnic blood flow; portal flow ~40%;
Useful in GIB;
Give with B-Blocker to avoid angina

15

Sodium Nitroprusside:
Mech: _ arteries and veins
Has _ toxicity

Relaxes arteries and veins;
has cyanide toxicity

16

Nitroglycerin primarily: _ (relaxes/constricts) _ (arteries/veins)

primarily relaxes veins

17

ASA
Mech: (Irreversible/reversible) binds _ (enzyme)
Effective for _ (time)

Irreversibly bind cyclooxygenase
effective for life of platelets (~7 days)

18

Indomethacin:
Mech: blocks _
Used to _

Blocks PG production, used to close PDA (effective in 70%); decr renal blood flow

19

Misoprostil:
Replaces _ (element) for patients taking _ in order to _

Replaces PGE2 (cytoprotective) for patient on NSAIDS in order to REDUCE PUD